House vacation rentals in Isle of Palms

Find and book unique houses on Airbnb

Top-rated house rentals in Isle of Palms

Guests agree: these houses are highly rated for location, cleanliness, and more.

Guest favorite
Home in Folly Beach
Steps 2 BEACH * *bright and airy cottage **
This home is 1 block off the beach. Enjoy a beach stay at this bright and airy cottage, Walk to Beach, Pier, Local Grocery, restaurants, and shops. We provide, 4 beach chairs, and 1 surfboard. This is a 2 bedroom, 1 bath home with fully equipped kitchen and open floor plan. Prepare to marvel over the spacious porch on the front of the home while enjoying the ocean breezes. Spacious outdoor shower, Huge back deck, a fire pit (firewood not included). *Please no animals due to family allergies*
Dec 14 – 21
$257 per night
4.86 out of 5 average rating, 205 reviews
Guest favorite
Home in Isle of Palms
Intracoastal water view luxurious family retreat
Enchanting house like no other on the island! Designed for guests who value a five-star experience. This luxury getaway is far from ordinary, it is simply perfect. - Right on the world-renowned Wild Dunes golf course - Only .5 mile from the beach -Enjoy FABULOUS SUNSET VIEWS OF THE INTRACOASTAL WATERWAY from the cozy porches - 3 king beds and 6 single bends - Soak away tension in our romantic 2-person tub or in the 8 person tub - Gym, infrared sauna - Game room: pool and Foosball
Nov 6 – 13
$655 per night
4.96 out of 5 average rating, 123 reviews
Guest favorite
Home in Isle of Palms
Beach House on IOP “Life of Sun, Sand & Sea"
'A few minutes' walk to the beach, this entire 2700 square feet house is spacious and perfect for families and friends. Enjoy a 12% discount for stays of 7 days or more, and a monthly discount of 20%. Take advantage of last-minute discounts as well. Recently, Isle of Palms (IOP) has added a beautiful boardwalk to the beach, enhancing convenience for your access to the beach. Welcome to 'Life of Sun, Sand & Sea', and enjoy your stay!
Feb 19 – 26
$198 per night
4.98 out of 5 average rating, 139 reviews

Popular amenities for Isle of Palms house rentals

House rentals with a pool

Guest favorite
Home in Mount Pleasant
Coastal Family Getaway, Heated Pool
Nov 3 – 10
$363 per night
4.94 out of 5 average rating, 199 reviews
Guest favorite
Home in Mount Pleasant
Pleasant Place: Newly Built with Pool: Close to downtown/beach
Oct 19 – 26
$686 per night
4.95 out of 5 average rating, 101 reviews
Guest favorite
Home in Mount Pleasant
Pura Vida, minutes to Beaches, w/a Pool!
Sep 12 – 19
$450 per night
4.97 out of 5 average rating, 115 reviews
Guest favorite
Home in Seabrook Island
Brand New Island Getaway
May 3 – 10
$455 per night
4.98 out of 5 average rating, 107 reviews
Guest favorite
Home in Saint Helena Island
The Hampton House
Nov 26 – Dec 3
$825 per night
4.99 out of 5 average rating, 104 reviews
Guest favorite
Home in Johns Island
Charleston, SC-2 BR Guest Suite w/ Separate Entry
Aug 14 – 21
$91 per night
4.88 out of 5 average rating, 384 reviews
Guest favorite
Home in Charleston
2500SF Downtown 1849 home w/ pool and roof deck!
Dec 16 – 23
$519 per night
4.97 out of 5 average rating, 202 reviews
Superhost
Home in Kiawah Island
Kiawah Island Home w/ Pool - 4 bedroom /4 bath
Dec 24 – 31
$612 per night
4.8 out of 5 average rating, 111 reviews
Guest favorite
Home in Charleston
Charleston Tranquil Marshside Retreat w/Pool/Spa
Aug 19 – 26
$379 per night
4.87 out of 5 average rating, 206 reviews
Guest favorite
Home in North Charleston
Gorgeous Executive Home on Pond *5 beds*
Jul 23 – 30
$246 per night
4.96 out of 5 average rating, 318 reviews
Guest favorite
Home in Charleston
Cozy home with pool & cat
Jun 2 – 9
$212 per night
4.94 out of 5 average rating, 125 reviews
Superhost
Home in Beaufort
Estate Living on 5 acres with pool in Beaufort, SC
Jan 7 – 14
$314 per night
4.89 out of 5 average rating, 143 reviews

Weekly house rentals

Guest favorite
Home in Folly Beach
Pelican's Porch on Folly Beach-Oceanview
May 18 – 23
$250 per night
4.91 out of 5 average rating, 237 reviews
Guest favorite
Home in Mount Pleasant
NEW upscale EARL CRT 3-bdrm Old Village/Shem Creek
Aug 18 – 25
$301 per night
5.0 out of 5 average rating, 174 reviews
Guest favorite
Home in Isle of Palms
Blue Star Beach House. BBQ/yard. Walk to beach!
Jul 8 – 15
$441 per night
4.95 out of 5 average rating, 110 reviews
Guest favorite
Home in Mount Pleasant
Trendy, Modern House Close to Beaches & Downtown
Jan 4 – 11
$220 per night
4.96 out of 5 average rating, 166 reviews
Guest favorite
Home in Mount Pleasant
Charming Charleston Getaway/Clean Modern & Coastal
Jul 12 – 19
$655 per night
5.0 out of 5 average rating, 104 reviews
Guest favorite
Home in Folly Beach
Arctic Palms is 2nd row with OCEAN VIEWS!
Apr 14 – 21
$489 per night
4.99 out of 5 average rating, 185 reviews
Guest favorite
Home in Mount Pleasant
Updated Charming Home, Close to Beach & Downtown
May 20 – 27
$356 per night
5.0 out of 5 average rating, 107 reviews
Guest favorite
Home in Mount Pleasant
Coastal Farmhouse Comfort
Oct 9 – 16
$267 per night
4.92 out of 5 average rating, 131 reviews
Guest favorite
Home in Summerville
Schoolhouse Cottage in Historic Summerville
Dec 4 – 11
$96 per night
4.97 out of 5 average rating, 247 reviews
Guest favorite
Home in Isle of Palms
★Stylish & Bright★ | Walk to Beach, Patio, Parking
Oct 6 – 13
$400 per night
4.97 out of 5 average rating, 74 reviews
Superhost
Home in Isle of Palms
Lee's Beach House
Aug 25 – Sep 1
$1,000 per night
4.9 out of 5 average rating, 96 reviews
Guest favorite
Home in Isle of Palms
Shep's Southern Charm Isle of Palms Beach Bungalow
Nov 21 – 28
$513 per night
5.0 out of 5 average rating, 24 reviews

Private house rentals

Guest favorite
Home in Isle of Palms
Fully renovated home- located 1 block from beach!
Apr 23 – 30
$479 per night
5.0 out of 5 average rating, 22 reviews
Guest favorite
Home in Isle of Palms
debbie's dream | Magnificent Oceanfront-Golf View
Feb 16 – 23
$626 per night
5.0 out of 5 average rating, 6 reviews
Guest favorite
Home in Isle of Palms
Bright, Spacious House Located 2 Blocks from Beach
Feb 15 – 22
$500 per night
4.92 out of 5 average rating, 64 reviews
Guest favorite
Home in Isle of Palms
Island House Isle of Palms
Nov 14 – 21
$561 per night
4.96 out of 5 average rating, 46 reviews
Guest favorite
Home in Isle of Palms
3 BR only 1 block to the beach!
Jul 15 – 22
$699 per night
5.0 out of 5 average rating, 22 reviews
Superhost
Home in Isle of Palms
Pet Friendly!!! 2 blocks from Beach - 1 house away from Park - 4 Bikes!!!
Sep 30 – Oct 7
$428 per night
5.0 out of 5 average rating, 11 reviews
Guest favorite
Home in Isle of Palms
A Golden Sunrise - An iTrip Vacations Home
Apr 8 – 15
$747 per night
5.0 out of 5 average rating, 6 reviews
Guest favorite
Home in Isle of Palms
The Crab Chateau - 3 Blocks to Beach
Nov 8 – 15
$356 per night
4.9 out of 5 average rating, 80 reviews
Guest favorite
Home in Isle of Palms
Serendipity By The Sea
Aug 18 – 25
$352 per night
4.82 out of 5 average rating, 11 reviews
Guest favorite
Home in Isle of Palms
Adorable cottage just 1 block to the beach!
Oct 10 – 17
$315 per night
4.96 out of 5 average rating, 48 reviews
Guest favorite
Home in Isle of Palms
Family Beach Cove on Golf Course in Wild Dunes
Oct 27 – Nov 3
$638 per night
5.0 out of 5 average rating, 16 reviews
Guest favorite
Home in Isle of Palms
Isle of Palms 3 BR 2 BA close to beach
Jan 3 – 10
$334 per night
4.88 out of 5 average rating, 17 reviews

Quick stats about house rentals in Isle of Palms

Total rentals

630 properties

Rentals with a pool

440 properties have a pool

Pet-friendly rentals

200 properties allow pets

Family-friendly rentals

620 properties are a good fit for families

Total number of reviews

7.6K reviews

Nightly prices starting at

$10 before taxes and fees

Destinations to explore