Apartment vacation rentals in Isle of Palms

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Top-rated apartment rentals in Isle of Palms

Guests agree: these apartments are highly rated for location, cleanliness, and more.

Guest favorite
Apartment in Mount Pleasant
The Coastal Getaway!
If you are looking for a vacation spot that is extremely clean, cozy, and ideally located, look no further than the Coastal Getaway! This unit, of which guests have exclusive use, is just a short drive to local beaches, and major eateries. Also, the famous Shem Creek & Marina, which offers kayaking, paddle boating, and waterfront restaurants, is about a mile away. Historic Downtown Charleston is a ten minute drive. Town of Mt. Pleasant STR License # : STR30244 Business License #: 20117415
Mar 25 – 30
$129 per night
4.92 out of 5 average rating, 251 reviews
Guest favorite
Apartment in Mount Pleasant
Lovely Garden Suite for One Guest. Bathrm/Parking
STR Lic# ST230023- Business Lic 20113222 Beautiful Garden Suite Room , private 3 piece bathroom and private entrance and garden space just can't be beat. Located in Old Village. 5 minutes to Beach, 10 to downtown Though there is a Queen Bed this to be for ONE GUEST ONLY. The room is very comfortable with Fridge, Coffee Maker and Microwave. There is a work desk and chair with a beautiful view of the garden. Located in Old Village. No TV, strong Wifi. Bicycle provided,safe neighborhood.
Feb 4 – 11
$85 per night
4.99 out of 5 average rating, 129 reviews
Guest favorite
Apartment in Mount Pleasant
Old Village Retreat-Shem Creek-Downtown CHS-Beach
Located perfectly in the Old Village neighborhood mins. from the buzz of downtown Charleston as well as the beaches of Sullivan's Island + Isle of Palms. This upscale apt. designed w/ style + comfort in mind has everything you will need for a relaxing stay in CHS. Walk or bike just a few blocks to nearby Shem Creek and experience the restaurants, shopping, bars, outdoor adventures such as kayaking, paddle boarding, boat charters, etc.+ take in the picturesque views of the Charleston Harbor.
Dec 8 – 15
$193 per night
4.99 out of 5 average rating, 166 reviews

Popular amenities for Isle of Palms apartment rentals

Weekly apartment rentals

Guest favorite
Apartment in Folly Beach
Steps from the beach - 1 bedroom - Folly Beach
Aug 7 – 14
$189 per night
4.96 out of 5 average rating, 366 reviews
Guest favorite
Apartment in Johns Island
Sailors Rest: Sauna & Pool, Johns Island
Sep 8 – 15
$195 per night
4.95 out of 5 average rating, 200 reviews
Guest favorite
Apartment in Mount Pleasant
Charming bungalow near beaches/downtown/Shem Creek
Jan 7 – 14
$102 per night
4.84 out of 5 average rating, 350 reviews
Guest favorite
Apartment in Charleston
Dream Catcher Carriage House Daniel Island
Aug 23 – 30
$131 per night
4.99 out of 5 average rating, 313 reviews
Guest favorite
Apartment in Folly Beach
Two Sisters Folly, Unit A- Marshfront Duplex
Oct 25 – Nov 1
$150 per night
4.9 out of 5 average rating, 162 reviews
Guest favorite
Apartment in Folly Beach
Chill Shack - 318 East Ashley
Nov 13 – 20
$198 per night
4.96 out of 5 average rating, 106 reviews
Guest favorite
Apartment in Mount Pleasant
Mt. Pleasant Charming Suite near Beach, Charleston
Aug 2 – 9
$148 per night
4.99 out of 5 average rating, 171 reviews
Guest favorite
Apartment in Mount Pleasant
Petit International Shem Creek Studio Walkable C
Nov 24 – Dec 1
$137 per night
4.87 out of 5 average rating, 317 reviews
Guest favorite
Apartment in Mount Pleasant
Lovely Guesthouse near Shem Creek
Jan 8 – 13
$145 per night
5.0 out of 5 average rating, 213 reviews
Guest favorite
Apartment in Folly Beach
Blackbeard's Folly I • Sleeps 6 • 500ft From Beach
Nov 19 – 26
$242 per night
4.91 out of 5 average rating, 314 reviews
Guest favorite
Apartment in Mount Pleasant
Historic Old Mt Pleasant Hideaway
Dec 28 – Jan 4
$213 per night
4.95 out of 5 average rating, 231 reviews
Guest favorite
Apartment in Charleston
Daniel Island Studio For Your Enjoyment!
Apr 12 – 19
$99 per night
4.9 out of 5 average rating, 220 reviews

Private apartment rentals

Guest favorite
Apartment in Edisto Island
424 Oristo Lodge
Jan 31 – Feb 7
$145 per night
4.93 out of 5 average rating, 202 reviews
Guest favorite
Apartment in Beaufort
Lady's Island Cottage
Oct 30 – Nov 6
$90 per night
4.98 out of 5 average rating, 248 reviews
Guest favorite
Apartment in Summerville
Private Apartment in Historic District
Apr 23 – 30
$85 per night
4.9 out of 5 average rating, 184 reviews
Guest favorite
Apartment in Folly Beach
Perfect spot to enjoy all that Folly Beach offers!
Mar 24 – 31
$188 per night
4.99 out of 5 average rating, 118 reviews
Guest favorite
Apartment in Folly Beach
Fantastic Vibe! Folly Vacation Apt D
Jan 26 – Feb 2
$117 per night
4.91 out of 5 average rating, 227 reviews
Guest favorite
Apartment in Charleston
Courtyard Suite with Tranquil Garden & Heated Pool
Nov 1 – 8
$280 per night
4.78 out of 5 average rating, 445 reviews
Guest favorite
Apartment in Charleston
Cool Studio Apt/Full Kitchen/Great Location!
Oct 7 – 14
$88 per night
4.9 out of 5 average rating, 203 reviews
Guest favorite
Apartment in Charleston
Private Suite C w/Private Entry, king size bed
Aug 12 – 19
$76 per night
4.88 out of 5 average rating, 405 reviews
Guest favorite
Apartment in Charleston
Modern Stylish 2b/2b Downtown near Upper King
Sep 12 – 19
$415 per night
4.98 out of 5 average rating, 108 reviews
Guest favorite
Apartment in Beaufort
The Harrington - Historic Downtown Beaufort
Dec 7 – 14
$125 per night
4.96 out of 5 average rating, 251 reviews
Guest favorite
Apartment in Folly Beach
Folly Beach HideAway
Feb 24 – Mar 1
$161 per night
4.99 out of 5 average rating, 190 reviews
Guest favorite
Apartment in Mount Pleasant
comfy cottage nestled in the old village
Dec 30 – Jan 6
$165 per night
4.9 out of 5 average rating, 433 reviews

Apartment rentals with a hot tub

Guest favorite
Apartment in Hanahan
Waterfront Private Hot Tub Fire Pit Dock Fishing A
Jul 30 – Aug 6
$236 per night
4.9 out of 5 average rating, 115 reviews
Guest favorite
Apartment in Edisto Island
Ocean Ridge Resort 1 Bedroom
Apr 15 – 22
$128 per night
5.0 out of 5 average rating, 6 reviews
Superhost
Apartment in Edisto Island
Edisto Beach 2BR Condo on Lovely Resort w/Amen.
$299 per night
New place to stay
Apartment in Hanahan
Pink Paradise 2-bedroom
Oct 16 – 23
$104 per night
4.57 out of 5 average rating, 7 reviews
Apartment in Charleston
Palm Vista
May 30 – Jun 6
$329 per night
5.0 out of 5 average rating, 4 reviews
Apartment in Edisto Island
Spacious 2BR @Ocean Ridge Resort
May 4 – 11
$294 per night
4.4 out of 5 average rating, 5 reviews
Apartment in Edisto Island
Alluring 3br Presidential @ Wyndham King Cotton
May 18 – 25
$439 per night
New place to stay
Superhost
Apartment in Edisto Island
Edisto Beach 2BR Condo on Lovely Resort w/Amen.
$289 per night
New place to stay
Superhost
Apartment in Edisto Island
Ocean Ridge Resort 1 Bedroom
Apr 11 – 18
$128 per night
New place to stay
Superhost
Apartment in Edisto Island
Ocean Ridge Resort 2 Bedroom
Apr 11 – 18
$213 per night
New place to stay
Apartment in Hanahan
Beautiful 3BR cottage house
Oct 30 – Nov 6
$149 per night
4.8 out of 5 average rating, 5 reviews
Apartment in Hanahan
BIG 3 bedroom unit
Aug 26 – Sep 2
$181 per night
4.88 out of 5 average rating, 25 reviews

Quick stats about apartment rentals in Isle of Palms

Total rentals

40 properties

Rentals with dedicated workspaces

10 properties have a dedicated workspace

Rentals with a pool

30 properties have a pool

Family-friendly rentals

20 properties are a good fit for families

Total number of reviews

760 reviews

Nightly prices starting at

$80 before taxes and fees

Destinations to explore