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South Carolina vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in South Carolina

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Shipping container in Walhalla
The Southern Cross at Hi Saw Gap
The quintessential Tiny Home experience at beautiful Hi Saw Gap! The Southern Cross is located cliff's edge with endless views over untouched natural beauty. Fabulous outdoor amenities compel you to be outside, including a glass enclosed shelter, propane fire pit, charcoal BBQ grill, and covered bistro deck with outdoor kitchen and prep station. Located just a half-mile from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park.
$128 per night
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Condo in Myrtle Beach
Luxury King OceanFront Suite
Oceanfront Private Condo! Wake up to the Ocean View! Newly remodeled Direct OCEANFRONT open floor-plan unit! Steps away from the beach! -King Bed -50" QLED Smart TV -Premium Cable -Electric Fireplace -Private Balcony with outdoor furniture -Stocked kitchen -Keyless Entry -Access to all Heated indoor/outdoor pools & jacuzzis. OPEN ALL YEAR -Located on 5th floor at Wyndham SeaWatch Resort 20 Min from the airport. 2 min drive to Tanger outlet mall, Walmart, restaurants/groceries, golf course.
$203 per night
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Shipping container in Walhalla
The Valhalla Sky Suite at Hi Saw Gap
Soar above the canopy of Sumter National Forest in this one of a kind container home, located 0.5 miles from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park. Unwind after a day of exploring the waterfalls and parks of Upstate SC in your private spa in the sky, or cash in every penny of your million dollar view from the balcony bar and deck. All are welcome!
$215 per night
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South Carolina beach vacation rentals

Condo in Murrells Inlet
You and Me by the Sea
$229 per night
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Condo in Pawleys Island
Oceanfront 1st Floor Condo In Gated Community
$231 per night
Condo in Myrtle Beach
Be One of the First! Newly Updated Sea Watch Condo
$140 per night
Condo in Myrtle Beach
Awesome Corner Wrap Around Balcony Condo Fireplace
$243 per night
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Condo in Hilton Head Island
Ocean Front Resort Villa
$156 per night
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Condo in Hilton Head Island
Beach Resort-OceanView Villa-Stylish Total Remodel
$206 per night
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Condo in Hilton Head Island
Beachfront Resort- KING Bed-Partial Ocean View
$156 per night
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Rental unit in Folly Beach
Stay @ "Little Drip"
$228 per night
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Cottage in Saint Helena Island
Cute Cottage Next to Hunting Island.
$131 per night
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Condo in Myrtle Beach
Couples Retreat - Remodeled Oceanfront Studio
$168 per night
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Condo in North Myrtle Beach
Bring your flip flops we have the rest! 52nd Ave
$65 per night
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Vacation home in Myrtle Beach
Oceanfront Balcony Penthouse @ Myrtle Beach Resort
$139 per night
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South Carolina winter vacation rentals

Shipping container in Easley
Luxe Shipping Container w/ King on Lakefront Farm
$266 per night
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Cottage in Hardeeville
Tranquil Savannah River Cottage w/ Views+Breakfast
$174 per night
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Tiny home in Greer
*BRAND NEW* Tiny Village Retreat
$75 per night
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Treehouse in Mountain Rest
THE BELLA LUNA Romantic Mountain Treehouse
$269 per night
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Cabin in Landrum
Pet Friendly Riverside Private Cabin
$169 per night
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Guesthouse in Bluffton
Bluffton's Tropical Carriage House Getaway
$100 per night
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Cottage in Beaufort
Cara May Cottage
$155 per night
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Cabin in Landrum
Lakeshore Cottage Lake Lanier | Privacy, Free Wifi
$67 per night
Private room in Summerville
Private Bedroom in beautiful home.
$56 per night
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Cabin in Tamassee
A Lakefront Tiny Cabin w/ Private Dock
$211 per night
Condo in Hilton Head Island
Ocean Front Resort Condo
$168 per night
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Rental unit in Bluffton
Bluffton Villa in the heart of the Promenade
$150 per night
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South Carolina summer vacation rentals

Condo in Myrtle Beach
Charming Oceanfront Suite, Make Memories Here!
$89 per night
Condo in North Myrtle Beach
Gorgeous Beachfront - Newly Remodeled
$185 per night
Cottage in North Charleston
New Modern Coastal Cottage in Historic Old Village
$132 per night
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Rental unit in Myrtle Beach
Carolinian Beach Resort 0903: Studio Oceanfront
$115 per night
Private room in Summerville
Cheerful and comfortable bedroom
$47 per night
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Guesthouse in North Charleston
Guestsuite getaway "A"
$69 per night
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Private room in North Charleston
Quaint single bedroom with shared hall bathroom.
$59 per night
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Hotel room in Murrells Inlet
The Inlet Cottage Guests Suite
$73 per night
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Rental unit in Bluffton
Lovely one Bedroom Carriage House, in Old Town.
$125 per night
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Condo in Myrtle Beach
Wake up to the ocean! Pristine and perfect for 2!
$163 per night
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Condo in Myrtle Beach
Oceanfront Renovated 2023 King Bed Pools Hot Tubs
$186 per night
Condo in Myrtle Beach
Beautiful Oceanfront Ultimate Couples Get-Away
$183 per night
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Your guide to South Carolina

Welcome to South Carolina

Weeping Spanish moss cloaks the cobblestone streets and historic homes of South Carolina’s oldest cities while its coast beckons travelers from near and far. South Carolina is one of the original 13 colonies of the United States, and it resisted British authority. Perched on the coast just north of Savannah, Charleston has been a major port city since the Spanish first settled the area in the 16th century, and was hotly contested territory in subsequent wars. Remnants of this history still stand in places like Fort Sumter and Fort Moultrie. South Carolina’s draws are heavily clustered around coastal areas like Hilton Head and Myrtle Beach — or on waterways that connect to the sea — but there’s plenty to do and see in its inland cities like the state capital of Columbia and the cultural hotbed of Greenville.


When is the best time to stay in a vacation rental in South Carolina?

As one of the southernmost states on the Eastern Seaboard, South Carolina maintains a mild climate year-round, making it an ideal destination no matter when you’re visiting. Summer months are popular at the beaches, so avoid booking a vacation rental for June, July, and August if you want to escape the crowds. Fall and spring are traditionally beautiful, and a bit cooler, though still T-shirt weather. Keep hurricane season in mind when planning your trip to South Carolina; it runs June through November along the Atlantic coast. Winter, which happens to overlap with oyster season, can be a pleasant time to visit due to the lack of crowds, though some businesses in coastal areas may close seasonally.


What are the top things to do in South Carolina?

Charleston

With its cobblestone streets and antebellum architecture, Charleston is one of the most charming cities in the American South. A peninsula town whose rivers empty into the Atlantic Ocean, it has a warm, welcoming vibe where visitors are treated like family, and just about anywhere you go somebody is eager to fill your cup with a heavy-handed pour of spiked sweet tea. If you want to combine urban travel with a beach getaway, Charleston is the place for you; its downtown core occupies a tight grid of streets and historic homes with thriving beach communities — Folly Island to the west and Isle of Palms and Sullivan’s Island to the east — on each side.

Congaree National Park

Wildlife enthusiasts, hikers, and paddlers will want to add South Carolina’s only national park, just south of Columbia, to their itinerary. The Congaree and Wateree rivers snake their way through the bottomland hardwood forest, part of the Congaree International Biosphere Reserve, making it a great place to observe the unique ecosystems by kayak via its waterways.

Greenville

In the northwestern corner of the Palmetto State near the Blue Ridge Mountains, Greenville is a melting pot of lifestyles: a city made for epicures and art lovers that also places heavy emphasis on outdoor living. While Falls Park on the Reedy is Greenville’s centerpiece, it’s not the only waterfall in town: Greenville boasts more than 30 breathtaking cascades, three state parks, and the 22-mile, multi-use Prisma Health Swamp Rabbit Trail.