Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Eutawville
5 out of 5 average rating, 12 reviewsShady Cove on Fountain Lake
Home in Summerton
5 out of 5 average rating, 96 reviewsCheerful 3 bedroom home on the lake
Home in Salem
4.99 out of 5 average rating, 118 reviewsKeowee Key Luxury Condo - Stunning Views!
Home in Westminster
4.99 out of 5 average rating, 101 reviewsDream Weaver: Lakefront• jacuzzi• dog friendly
Home in Chapin
4.94 out of 5 average rating, 83 reviewsLake Murray: Panoramic Views, Kayaks & Hot Tub
Home in Chapin
5 out of 5 average rating, 10 reviewsFamily Ties Lakeside Retreat
Home in Irmo
4.87 out of 5 average rating, 105 reviewsLakefront w pool, dock and pool table, sleeps12
Home in Inman
4.95 out of 5 average rating, 111 reviewsCasa del Lago...Come Relax...You are on Lake Time!
Pet-friendly lake house rentals
Home in Saluda County
5 out of 5 average rating, 37 reviewsLake Murray Paradise/Lakefront/Dock/Wifi/Sunrise
Home in Seneca
4.94 out of 5 average rating, 109 reviewsGetaway on Lake Hartwell: Pontoon Rental, Clemson
Home in Hilton Head Island
4.93 out of 5 average rating, 107 reviewsCozy Coastal Chic - Beach, Pickleball, Golf, Pets
Home in Anderson
4.99 out of 5 average rating, 191 reviewsLake Escape
Home in Easley
4.91 out of 5 average rating, 145 reviewsLarge lake house - 15 min to Downtown Greenville
Home in Myrtle Beach
4.87 out of 5 average rating, 215 reviewsCozy Beach Paradise in Ocean Lakes | Outdoor TV
Home in Modoc
4.93 out of 5 average rating, 109 reviewsIvy’s Escape (water front) at Lake Thurmond
Home in Bluffton
4.98 out of 5 average rating, 149 reviewsOld Town Bluffton Cottage + FREE Golf Cart!
Private lake house rentals
Home in Hilton Head Island
5 out of 5 average rating, 49 reviews6 BR, Sleeps 26, Beach Time
Home in Six Mile
4.95 out of 5 average rating, 57 reviewsLake Keowee Beach Club Cabin
Home in Gilbert
5 out of 5 average rating, 16 reviewsTranquility
Home in Anderson
4.98 out of 5 average rating, 53 reviewsThe Shanty on Waites
Home in Cross Hill
4.95 out of 5 average rating, 20 reviewsLakeview Oasis with fire pit & hot tub!
Home in Anderson
4.96 out of 5 average rating, 85 reviewsSunset Point-Best view on Broadway - HOT TUB!
Home in Seneca
4.88 out of 5 average rating, 16 reviewsCozy Clemson Lake Getaway with Dock Access
Home in Lexington
5 out of 5 average rating, 21 reviewsSunrise and Sunset on the Lake
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