Villa vacation rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Villa rentals with a pool
Villa in Seabrook Island
5.0 out of 5 average rating, 12 reviewsClose to beach, pools,golf & tennis+Amenity Card*
Apr 6 – 13
Villa in Saint Helena Island
4.99 out of 5 average rating, 70 reviewsLittle Palm Villa | Oceanfront
Apr 7 – 14
Villa in Saint Helena Island
4.99 out of 5 average rating, 80 reviewsSandy Toes Condos
Oct 21 – 28
Villa in Seabrook Island
4.9 out of 5 average rating, 31 reviewsUpscale Villa, Amenity Included! Dog Friendly
Jan 16 – 23
Villa in Seabrook Island
4.83 out of 5 average rating, 59 reviewsPrivate island villa with luxury resort amenities!
Nov 2 – 9
Villa in Seabrook Island
4.85 out of 5 average rating, 33 reviewsSeabrook Golf View Villa: Pickleball, Pool & Bike
Aug 2 – 9
Villa in Seabrook Island
4.92 out of 5 average rating, 52 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Sep 15 – 22
Villa in Folly Beach
4.84 out of 5 average rating, 61 reviews83 Waters Edge - Comfy Cool - Pool
Jan 14 – 21
Private villa rentals
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Feb 15 – 22
Villa in Seabrook Island
4.57 out of 5 average rating, 7 reviewsBeach and Golf Paradise | Vaughan Villa
Jan 19 – 26
Villa in Edisto Island
4.73 out of 5 average rating, 52 reviewsLoft-e-Lagoon *No Cleaning Fee*
Jan 29 – Feb 5
Villa in Kiawah Island
4.93 out of 5 average rating, 96 reviewsClean & Comfortable! Steps to the beach!
May 12 – 19
Villa in Kiawah Island
4.97 out of 5 average rating, 88 reviewsLagoon view villa with office, easy walk to beach!
Jun 4 – 11
Villa in Edisto Island
4.97 out of 5 average rating, 36 reviewsRelax in a Happy Place
Jan 28 – Feb 4
Villa in Seabrook Island
4.86 out of 5 average rating, 51 reviews711 Spinnaker centrally located to EVERYTHING!
Jul 20 – 27
Villa in Isle of Palms
4.77 out of 5 average rating, 47 reviewsUpdated 2BR | Balcony | Pool | Dock
Oct 19 – 26
Luxury villa rentals
Villa in Johns Island
4.75 out of 5 average rating, 4 reviewsOceanfront! Renovated, Easiest Beach Access
Oct 10 – 17
Villa in Seabrook Island
4.91 out of 5 average rating, 11 reviewsLuxury Seabrook Isl Beach Condo
Oct 5 – 12
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Feb 12 – 19
Villa in Kiawah Island
5.0 out of 5 average rating, 15 reviewsOceanfront Windswept Villa
Aug 23 – 30
Villa in Isle of Palms
5.0 out of 5 average rating, 4 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Apr 18 – 25
Villa in Kiawah Island
4.89 out of 5 average rating, 18 reviewsSpacious Penthouse 3BR 3Bath Villa with Ocean View
Feb 18 – 25
Villa in Kiawah Island
4.94 out of 5 average rating, 52 reviewsOpen floor plan 2 Bedroom Turtle Cove Villa
Dec 21 – 28
Villa in Seabrook Island
A Coastal Oasis! 2BR Atrium! Golf/Lagoon Views!
Aug 4 – 11
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$170 before taxes and fees
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- Rentals with outdoor seating Isle of Palms
- Rentals with pools Isle of Palms
- Rentals with a patio Isle of Palms
- Waterfront rentals Isle of Palms
- Fitness-friendly rentals Isle of Palms
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- Rentals with a kayak Isle of Palms
- Beach condo rentals Isle of Palms
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- Rentals with a hot tub Isle of Palms
- Monthly Rentals Isle of Palms
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- Rentals with beach access Isle of Palms
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