Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Park Circle
4.94 out of 5 average rating, 362 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in James Island
4.92 out of 5 average rating, 317 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Park Circle
5 out of 5 average rating, 124 reviewsThe Park Circle Clerestory Studio Guest House
Guesthouse in Charleston
4.99 out of 5 average rating, 270 reviewsSpacious Daniel Island Apartment
Guesthouse in Ridgeville
4.82 out of 5 average rating, 219 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in West Ashley
4.95 out of 5 average rating, 347 reviewsThe White House of Avondale
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 235 reviewsGreen Garden Studio @greengardenstudio2017
Guesthouse in Summerville
4.95 out of 5 average rating, 223 reviewsNina's Cottage -Historic Downtown Summerville
Guest house rentals with a patio
Guesthouse in West Ashley
4.95 out of 5 average rating, 104 reviewsBoHo styled casita in adorable neighborhood...
Guesthouse in West Ashley
4.96 out of 5 average rating, 141 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Park Circle
4.9 out of 5 average rating, 101 reviewsMy Happy Place
Guesthouse in James Island
4.84 out of 5 average rating, 116 reviewsGuest Suite by the Beach
Guesthouse in Johns Island
4.9 out of 5 average rating, 127 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in West Ashley
4.98 out of 5 average rating, 139 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Hanahan
4.99 out of 5 average rating, 98 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Goose Creek
4.95 out of 5 average rating, 58 reviewsThe Blue Secret
Guest house rentals with a washer and dryer
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 268 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Guesthouse in West Ashley
4.9 out of 5 average rating, 571 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Charleston
4.98 out of 5 average rating, 250 reviewsDetached Guest Suite
Guesthouse in Park Circle
4.95 out of 5 average rating, 128 reviewsNewly Renovated Studio in Park Circle
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 452 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 232 reviewsCozy Apartment in Mount Pleasant
Guesthouse in West Ashley
4.99 out of 5 average rating, 161 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in James Island
5 out of 5 average rating, 153 reviewsThe Guesthouse at Old Orchard
Quick stats about guesthouse rentals in Charleston
Total rentals
220 properties
Total number of reviews
24K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
100 properties have a dedicated workspace
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