Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
5.0 out of 5 average rating, 110 reviewsThe Park Circle Clerestory Studio Guest House
Jun 20 – 27
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 220 reviewsGreen Garden Studio @greengardenstudio2017
Oct 15 – 22
Guesthouse in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
Oct 21 – 28
Guesthouse in North Charleston
4.86 out of 5 average rating, 441 reviewsPark Circle Jungalow Loft
Sep 9 – 16
Guesthouse in Johns Island
4.98 out of 5 average rating, 238 reviewsPrivate waterfront apt in the oaks
Mar 30 – Apr 6
Guesthouse in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
Oct 1 – 8
Guesthouse in Summerville
4.87 out of 5 average rating, 748 reviewsNew Loft in Historic Summerville
Jan 16 – 23
Guesthouse in Charleston
4.93 out of 5 average rating, 316 reviewsCozy Island Cottage
Nov 26 – Dec 3
Guest house rentals with a patio
Guesthouse in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
Mar 10 – 17
Guesthouse in Charleston
4.98 out of 5 average rating, 122 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Apr 6 – 13
Guesthouse in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
Aug 2 – 9
Guesthouse in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
Aug 6 – 13
Guesthouse in Charleston
4.94 out of 5 average rating, 78 reviewsSpacious 1 bedroom cottage in Avondale
Mar 24 – 31
Guesthouse in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
Jun 18 – 25
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 26 reviewsCoastal Charm: Village Hideaway
Dec 14 – 21
Guesthouse in Charleston
5.0 out of 5 average rating, 12 reviewsLowcountry Guesthouse
Jul 15 – 22
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
Mar 4 – 11
Guesthouse in Charleston
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
Oct 4 – 11
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 436 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Nov 2 – 9
Guesthouse in Charleston
4.98 out of 5 average rating, 106 reviewsCharleston Casita near Folly Beach *Dog Friendly*
Dec 1 – 8
Guesthouse in Charleston
4.9 out of 5 average rating, 548 reviewsCute, Cozy, Charleston Cottage
Sep 25 – Oct 2
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 248 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Jul 5 – 12
Guesthouse in Charleston
4.99 out of 5 average rating, 141 reviewsLarge Guesthouse with Private Dock & Marsh Views
Dec 4 – 11
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 117 reviewsBeach, downtown, Alhambra Hall weddings so close!
Aug 5 – 12
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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