Guesthouse vacation rentals in Charleston County
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Top-rated guesthouse rentals in Charleston County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Charleston County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 362 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.92 out of 5 average rating, 317 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in North Charleston
5 out of 5 average rating, 124 reviewsThe Park Circle Clerestory Studio Guest House
Guesthouse in Ridgeville
4.82 out of 5 average rating, 219 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Summerville
4.95 out of 5 average rating, 223 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Charleston
4.95 out of 5 average rating, 347 reviewsThe White House of Avondale
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 235 reviewsGreen Garden Studio @greengardenstudio2017
Guesthouse in Charleston
4.91 out of 5 average rating, 662 reviewsIsland Oasis—Near Downtown
Guest house rentals with a patio
Guesthouse in Charleston
4.95 out of 5 average rating, 104 reviewsBoHo styled casita in adorable neighborhood...
Guesthouse in Charleston
4.96 out of 5 average rating, 141 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in North Charleston
4.9 out of 5 average rating, 101 reviewsMy Happy Place
Guesthouse in Charleston
4.98 out of 5 average rating, 139 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Charleston
4.84 out of 5 average rating, 116 reviewsGuest Suite by the Beach
Guesthouse in Johns Island
4.9 out of 5 average rating, 127 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Goose Creek
5 out of 5 average rating, 12 reviewsDreams
Guesthouse in Goose Creek
4.95 out of 5 average rating, 58 reviewsThe Blue Secret
Guest house rentals with a washer and dryer
Guesthouse in North Charleston
4.95 out of 5 average rating, 128 reviewsNewly Renovated Studio in Park Circle
Guesthouse in Charleston
4.9 out of 5 average rating, 571 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 268 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 232 reviewsCozy Apartment in Mount Pleasant
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 452 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Charleston
4.99 out of 5 average rating, 161 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 268 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Guesthouse in Charleston
5 out of 5 average rating, 153 reviewsThe Guesthouse at Old Orchard
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