House vacation rentals in Panama
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Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 138 reviewsVilla Isabella in Coronado Beach Panama
Sep 20 – 27
Home in contadora
4.85 out of 5 average rating, 193 reviewsvilla in counter, pearls
Oct 3 – 10
Home in Playa Mata Oscura
4.92 out of 5 average rating, 25 reviewsCasa De Ola, Jungle Beach Cabin
Apr 21 – 28
Home in Playa Venao
5.0 out of 5 average rating, 15 reviewsCasa Samambaia - sea view tropical paradise w pool
Jun 16 – 23
Home in San Carlos
4.93 out of 5 average rating, 87 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Sep 1 – 8
Home in Playa Bluff
5.0 out of 5 average rating, 15 reviewsJungle House 100m from the beach
Dec 2 – 9
Home in Bocas del Toro Province
5.0 out of 5 average rating, 8 reviewsThe Pool House, Beach House on Paunch Beach
Nov 22 – 29
Home in Bocas Del Toro
4.96 out of 5 average rating, 90 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Sep 17 – 24
Weekly house rentals
Home in Bocas del Toro
5.0 out of 5 average rating, 9 reviewsLa Casita Barrbra BnB
Jun 12 – 19
Home in Santa Catalina
5.0 out of 5 average rating, 25 reviewsCasa Colibrí - modern house in the green
Apr 12 – 19
Home in Boquete
5.0 out of 5 average rating, 12 reviewsCaturra Casita @ Finca Panda
Oct 11 – 18
Home in Torio
5.0 out of 5 average rating, 13 reviewsIdeal Creative Retreat Immersed in Forest
Apr 24 – May 1
Home in Panamá
5.0 out of 5 average rating, 8 reviewsUnique 4 room house - direct access to the beach
Apr 17 – 24
Home in Corregimiento de Isla Grande
4.96 out of 5 average rating, 83 reviewsPuntita Manzanillo, fantastic sea and jungle
Nov 30 – Dec 7
Home in Bocas del Toro
5.0 out of 5 average rating, 21 reviewsTropical Paradise, Oceanfront Home in the Jungle
Sep 10 – 17
Home in Boquete
5.0 out of 5 average rating, 64 reviewsAlba Verde Guest House, Private Vacation Rental
Nov 23 – 30
Private house rentals
Home in Bajo Boquete
4.96 out of 5 average rating, 57 reviewsSpacious 3BR walking distance, close to everything
May 25 – Jun 1
Home in Bocas del Toro
5.0 out of 5 average rating, 17 reviewsCasa del Fuego - Caribbean Beachfront Magic!
Oct 20 – 27
Home in Chame
4.92 out of 5 average rating, 12 reviewsEscape the city! Cozy weather and home.
Jan 27 – Feb 3
Home in Los Algarrobos
4.96 out of 5 average rating, 85 reviewsCozy and relaxing house with terrace
Sep 9 – 16
Home in Cacique
5.0 out of 5 average rating, 19 reviewsEl Paraiso
Jan 31 – Feb 7
Home in Chame
5.0 out of 5 average rating, 11 reviewsP/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath
Jul 9 – 16
Home in Provincia de Panamá Oeste
4.88 out of 5 average rating, 16 reviewsLuxurious beach front home in Veracruz
Oct 24 – 31
Home in Alto Quiel
4.89 out of 5 average rating, 18 reviewsCasita Colibrí - with beautiful mountain views
Aug 29 – Sep 5
Destinations to explore
- Guesthouse rentals Panama
- Rentals with a home theater Panama
- Serviced apartment rentals Panama
- Mansion rentals Panama
- Island rentals Panama
- Farmstay rentals Panama
- Ski-in/ski-out rentals Panama
- Monthly Rentals Panama
- Rentals with a washer and dryer Panama
- Tiny house rentals Panama
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- Smoking-friendly rentals Panama
- Nature eco lodge rentals Panama
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- Fitness-friendly rentals Panama
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- Rentals with breakfast Panama
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- Chalet rentals Panama
- Rentals with a fireplace Panama
- Rentals with beach access Panama
- Bungalow rentals Panama
- Vacation home rentals Panama
- Treehouse rentals Panama
- Kid-friendly rentals Panama
- Pet-friendly rentals Panama
- Boutique hotel rentals Panama
- Rentals with an accessible height bed Panama
- Rentals with pools Panama
- Townhouse rentals Panama
- Rentals with lake access Panama
- Condo rentals Panama
- Apartment rentals Panama
- Cottage rentals Panama
- Beach condo rentals Panama
- Boat rentals Panama
- Cabin rentals Panama
- Rentals with a patio Panama
- Private suite rentals Panama
- Wheelchair accessible rentals Panama
- Waterfront rentals Panama
- Rentals with a hot tub Panama
- Rentals with a sauna Panama
- Beachfront rentals Panama
- Rentals with an EV charger Panama
- Bed and breakfasts Panama
- Rentals with outdoor seating Panama
- Rentals with a kayak Panama
- Villa rentals Panama
- House rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
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