Boutique hotel vacation rentals in Panama

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Panama

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Superhost

Hotel room in Bajo Boquete

4.92 out of 5 average rating, 107 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Hotel room in Playa coronado

4.91 out of 5 average rating, 32 reviews

EXCLUSIVE & PRIVATE OASIS CASA SWELL CORONADO -12+

Situated in the heart of Playa Coronado, this brand new exclusive and sophisticated boutique hotel offers a huge pool with exterior beds at only 350m from the beach. With only 4 bedrooms, we can focus on service and attention to customers to help them get the most out of Coronado and his surroundings. Whether you are on vacation or on a relocation trip, we are here to answer your questions over Panama and we can help you organized your whole panamanian discovery trip ! Adults and teens ONLY.

Superhost

Hotel room in PA

4.84 out of 5 average rating, 45 reviews

Rancho Cabaña- Private Porch, Loft, 1 min to beach

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Superhost

Hotel room in PA

4.9 out of 5 average rating, 29 reviews

Villa Coco King Room

Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Guest favorite

Hotel room in Bastimentos Island

4.95 out of 5 average rating, 63 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Guest favorite

Hotel room in Bocas del Toro Province

4.92 out of 5 average rating, 71 reviews

Economy Oceanview Room 1

Bird Island Bungalows is a hidden, secluded beach hotel surrounded by pristine private beaches, jungle and a 3.5ha lush tropical garden. From breathtaking sunsets from our 360 degree view roof top bar, silent meditation on our oceanview yoga deck, kayak tours to the bird watcher's paradise Bird Island to educational jungle walks to explore all the unique tropical flora and fauna - there is something for everyone or you just enjoy the beautiful silent sounds of nature and waves.

Hotel room in San Carlos

4.81 out of 5 average rating, 106 reviews

B) Beach, surf and Relax with King size bed

Manglar Lodge is a small beach Hotel located at El Palmar beach on the Pacific coast on the town of San Carlos, If you like nature and comfort, you'll enjoy your stay at Manglar Lodge We are small beach hotel that offers the visitor four cozy and clean rooms, WiFi, restaurant (open form 8.30am until 9pm) with great food and a great selection of craft beer and live music on some weekends from 7pm to 9.30pm The Room is on a 1 floor you have to walk up the stairs

Guest favorite

Hotel room in Playa Venao

5 out of 5 average rating, 7 reviews

Palmas Room - Tranquil Space with King Bed

This 2 person room is wonderful for calm and relaxation. With beautiful rustic decor, a comfortable king bed, A/C, hot/cold water, mini fridge, smart tv (ready for your streaming login), this room will allow you to wash away the salt and sand and relax after fun days surfing and laying on the beach. *Additional guest, available to kids up to 12 years old.* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host.*

Hotel room in Contadora Island

4.85 out of 5 average rating, 48 reviews

Luxury "LaRomantica" B&B A/C Jacuzzi Island-Tour !

The guesthouse "La Romantica" welcomes you warmly on the island of Contadora in the middle of the Pearl Islands ! Newly renovated, modern and functional. La Romantica is located only a few minutes walk from the nearest beach. Perhaps the most beautiful beach (Playa Casique) is only 750 meters away. Large flat screen Smart TV 2 Large terraces with integrated jacuzzi Strong free wifi Exceptional and rich breakfast (not included in the price)

Superhost

Hotel room in Bajo Boquete

4.77 out of 5 average rating, 81 reviews

Buena Vista Boquete Quadruple Room

This quadruple room is furnished with one double bed and two twin beds, all with semi-orthopedic mattresses. The room has a WiFi access, a Smart TV, large windows to enjoy the mountain view and a private bathroom. Features: Large windows / Bathroom / Access to rooftop patio with 360° views / Access to kitchen / WiFi / Smart TV / Standing fan / Parking

Superhost

Hotel room in Cambutal

4.89 out of 5 average rating, 9 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Guest favorite

Hotel room in Panamá

4.87 out of 5 average rating, 39 reviews

Private rooms Sofia's B&B Hostal Boutique

Boutique hostel accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The fee shown by Airbnb for your reservation distributes 2 guests per room, that is, guests must share beds and/or rooms. If you require a special room distribution for your group, please contact the host first, as the rate may vary.