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Hotel vacation rentals in Panama City
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Panama City
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City hotel rentals
Family-friendly hotel rentals
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Hotel room in San Felipe
4.9 out of 5 average rating, 48 reviewsBeautiful Boutique Apart-hotel view & services
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Private room in ciudad de panama
4.23 out of 5 average rating, 13 reviewsPrivate Double Room. Hab #5.
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Private room in Panamá
Villa Grande Hostel - Room 5
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Private room in Panamá
4.17 out of 5 average rating, 6 reviewsBetween 2 Aguas Hostel
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Hotel room in San Felipe
4.89 out of 5 average rating, 38 reviewsBoutique apart-hotel- Heart Old City
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Hotel room in San Felipe
5 out of 5 average rating, 33 reviewsHeart of the Old Town: Unique Boutique ApartHotel
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Hotel room in San Felipe
4.92 out of 5 average rating, 48 reviewsBeautiful boutique Apart-hotel-views and service
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Hotel room in San Felipe
4.95 out of 5 average rating, 43 reviewsBoutique apart-hotel - Old town center
Hotel rentals with a pool
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Hotel room in El Cangrejo
4.75 out of 5 average rating, 12 reviewsDouble-Apartment Hotel Principe Suite
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Hotel room in Panamá
4.94 out of 5 average rating, 35 reviewsVilla Royale
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Hotel room in Panamá
4.53 out of 5 average rating, 68 reviewsSelina Casco Viejo Panama City - Standard Room
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Hotel room in Panamá
4.41 out of 5 average rating, 17 reviewsRainforest Suite with Breakfast! 15 min from city
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Hotel room in Panamá
5 out of 5 average rating, 3 reviewsPrivate Room 2 Twin Beds
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Hotel room in Panamá
Jr. Suite Rm #2- Cerro Azul
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Private room in Panamá
1 Double Bed Room (1 to 2 people)
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Hotel room in Obarrio
Room in the City
Hotel rentals with a patio
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Hotel room in Punta Pacifica
5 out of 5 average rating, 3 reviewsEshel Panama Suites, Atlantic suite 04
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Private room in Punta Pacifica
Casa Orquídea Panama City #2
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Private room in Panamá
Parrot Suite Treehouse Cerro Azul
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Hotel room in Panamá
New place to stayCity Center. Deluxe Hostel Room
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Private room in Panamá
New place to stayORHO airport with transport free
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Private room in Panamá
Private space with bathroom 0 noise, 100% security
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Hotel room in Panamá
Beautiful apartment Privado in Casco Antiguo
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Hotel room in Panamá
Charming Hotel in Casco Viejo Corner Suite
Quick stats about hotel rentals in Panama City
Total rentals
120 properties
Nightly prices starting at
$10 before taxes and fees
Total number of reviews
2K reviews
Pet-friendly rentals
10 properties allow pets
Rentals with a pool
50 properties have a pool
Rentals with dedicated workspaces
90 properties have a dedicated workspace
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