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Panama City beach vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Condo in El Cangrejo
Apartment with 2 balconies overlooking Downtown
Everything is nearby in this home. It is strategically located Obarrio, in the heart of downtown Panama. Close to restaurants, bars, shops and supermarkets. One block away you will have the Via Argentina Metro Station where you will find quality nightlife. Two blocks away is the Sortis hotel, which has a Casino. You will have quick access to the roads that take you to get to know the Panama Canal, Amador or Causeway, Old Town and shopping centers such as Albrook mall and Multiplaza.
$58 per night
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Serviced apartment in Marbella
Cozy apartment | Quartier Marbella D
A wonderful and very well located building, which provides comfort in all aspects, in the center of Panama City, between Calle 47 and Calle 53, Marbella East, in a residential area full of life, large green areas, shopping malls and next to the business and financial entities area, with everything organized for the best stay for you and your beloved ones, in large and spacious apartments of up to 160m2 on some of its 25 levels.
$80 per night
Condo in Marbella
★★★★★Luxury 1 bedroom apt free parking & balcony
Panama is a vibrant, passionate and cosmopolitan city that radiates modernism and opportunity. With its modern creative energy, business opportunity, electric nightlife, unique traditions and extensive natural beauty, it is one of the most exciting capitals to discover. We offer you an exclusive and functional Boutique Apt in the heart of Panama City where fun and enjoyment are just a few steps away!
$63 per night
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Stay near Panama City's top sights

Photo of Multiplaza Panamá
Multiplaza Panamá147 locals recommend
Photo of Albrook Mall
Albrook Mall132 locals recommend
Photo of Causeway Amador
Causeway Amador67 locals recommend
Photo of Trump International Hotel & Tower Panama
Trump International Hotel & Tower Panama10 locals recommend
Photo of AltaPlaza Mall
AltaPlaza Mall38 locals recommend
Photo of Panama Viejo
Panama Viejo89 locals recommend

Panama City vacation rentals

Rental unit in Panamá
Charming one studio apartment center Casco Viejo
$54 per night
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Private room in Panama City
4-B Private room Old Town Apartment
$33 per night
Loft in El Cangrejo
Cozy Apartment with Balcony, Downtown-PTY Loft
$53 per night
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Private room in Panamá
4-A Old City Private Room
$35 per night
Private room in El Cangrejo
vip-full room, in beautiful-shared-apartment
$24 per night
Loft in El Cangrejo
Loft in the heart of the city
$53 per night
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Private room in Panamá
Private room with ocean view in Panama
$39 per night
Rental unit in El Cangrejo
Beautiful apartment in Via Argentina
$34 per night
Private room in Panamá
Ocean 3 Private Room
$23 per night
Condo in Panamá
Amazing Apt Steps from Casco Viejo in Panamá City
$54 per night
Rental unit in Marbella
Best Location Rental Apartment
$69 per night
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Serviced apartment in Panamá
Studio apartment, contemporary style. Nuevo
$60 per night
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