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Vacation rentals in Panama City

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Condo in Panamá
The Abstract Art Condo By AcoModo
La Cuadra is one of the most luxurious buildings in casco, with an amazing rooftop pool featuring a privileged stunning 360 view of the city skyline and pacific bay on one side, and the Panama Canal entry and Cerro Ancon on the other. The building has all the amenities for every client to experience a great stay in Casco Viejo. La Cuadra offers the best combination of amenities and central location, which is ideal to discover and enjoy the best of what Casco has to offer.
$96 per night
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Rental unit in Panamá
Design Pool and 180º Rooftop N2
Apartment recently renovated and decorated by an international designer, on the main avenue of Casco Viejo (nocturnal silence area) with views of the church and the most beautiful existing ruins. In addition to a 180º rooftop with an infinity pool. One bedroom apartment with double queen bed, living room, dining room, kitchen, beautiful bathroom, 55" Smart Tv, private balcony with views of the Church, etc. ► Silent air conditioning ►Rain shower
$91 per night
Rental unit in Panamá
Apartment with pool front the National Theater Di2
Be The First GUESTS Design apartment and fully equipped and with pool. You have a pool at the door of the apartment to spend an incredible stay. Master bedroom with king bed, living room with double sofa bed, kitchen, bathroom, very bright, smart tv, etc. ► Silent air conditioning in all rooms. ► Smart Tv with 2000 channels in all rooms ►Living room: bright living room completely renovated with designer furniture and hundreds of details.
$80 per night

Stay near Panama City's top sights

Photo of Albrook Mall
Albrook Mall132 locals recommend
Photo of Multiplaza Panamá
Multiplaza Panamá147 locals recommend
Photo of Causeway Amador
Causeway Amador67 locals recommend
Photo of AltaPlaza Mall
AltaPlaza Mall38 locals recommend
Photo of Miraflores Locks
Miraflores Locks216 locals recommend
Photo of Trump International Hotel & Tower Panama
Trump International Hotel & Tower Panama10 locals recommend

Other great vacation rentals in Panama City

Condo in Marbella
Av. Balboa, very high floor, luxury
$75 per night
Rental unit in Panamá
Design Pool and 180º Rooftop N3
$91 per night
Rental unit in Panamá
w* | Artistic 1BR in Casco Viejo
$66 per night
Rental unit in Marbella
★★★★★Luxury 1 bedroom apt with free parking
$58 per night
Rental unit in Panamá
Modern apartment with gorgeous sea view
$85 per night
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Serviced apartment in Panamá
Stunning Sea View apt at city center
$88 per night
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Rental unit in Marbella
Ocean Front Apartment in the Best Location
$86 per night
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Rental unit in Panamá
w*| Modern 1BR With Rooftop Pool In Casco Antiguo
$62 per night
Rental unit in Panamá
Completely renovated apartment with jacuzzi P8
$71 per night
Condo in Panama
Cozy Quiet CASCO VIEJO Boutique Studio with King
$91 per night
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Rental unit in Panamá
Apartment in Banking Area
$60 per night
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Condo in Panamá
The Stylish Condo by AcoModo
$86 per night
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Stays in Costa del Este

Rental unit in Costa del Este
Amazing Luxury Junior Penthouse Panoramic Views
$169 per night
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Private room in Panama City
Accommodation with Views in Costa del Este 1
$28 per night
Rental unit in Costa del Este
Beautiful apartment on the east coast
$80 per night
Condo in Panamá
Entire apartment! 10 minutes from the airport
$120 per night
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Stays in El Cangrejo

Rental unit in El Cangrejo
The Comic Pop Studio by AcoModo
$46 per night
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Rental unit in El Cangrejo
Full Loft - On Via Argentina El Cangrejo 250 Mbps
$38 per night
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Condo in El Cangrejo
R.1102 Nice executive studio in tourist area.
$52 per night
Rental unit in El Cangrejo
Beautiful loft in Via Argentina
$39 per night

Stays in Punta Paitilla

Rental unit in Punta Pacifica
COZY APARTMENT IN PUNTA PACIFICA
$59 per night
Serviced apartment in Punta Pacifica
Hermoso apart en Ciudad de Panamá piso 2-C
$67 per night
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Rental unit in Marbella
Ocean Front Apartment, Best PTY Location
$99 per night
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Rental unit in Marbella
105m2 Luxury apartm in Bayfront Tower
$68 per night
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