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House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool
![](https://a0.muscache.com/im/pictures/hosting/Hosting-809741172674277938/original/52f44249-dfe4-4ed0-b2c0-5ceca58564bb.jpeg?im_w=720)
Home in Provincia de Panamá Oeste
4.86 out of 5 average rating, 22 reviewsLuxurious beach front home in Veracruz
![](https://a0.muscache.com/im/pictures/hosting/Hosting-596480149557122404/original/ab5d1c2e-820e-4191-833c-b7133d1ba6af.png?im_w=720)
Home in Panama City
4.91 out of 5 average rating, 23 reviewsCheerful Casa Duplex with swimming pool.
![](https://a0.muscache.com/im/pictures/miso/Hosting-960278368785038608/original/a2e8010b-cd96-4c52-ae74-9502050a103b.jpeg?im_w=720)
Home in Panamá
4.82 out of 5 average rating, 22 reviewsHummingbird House/Casa de Colibri
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Home in Panamá
New place to stayPanama - amazing view!
![](https://a0.muscache.com/im/pictures/miso/Hosting-46483901/original/ea6b689d-f890-439e-a140-8883cf3b1b57.jpeg?im_w=720)
Home in Panamá
4.75 out of 5 average rating, 36 reviewsPrivate Pool House with BBQ and more
![](https://a0.muscache.com/im/pictures/miso/Hosting-1125621665967646026/original/3784ae37-87c6-4cea-88fe-56a64752e493.jpeg?im_w=720)
Home in Vacamonte
5 out of 5 average rating, 8 reviewsRelax beach House
![](https://a0.muscache.com/im/pictures/29d72c85-7bf6-4df2-b22c-05823cfb7672.jpg?im_w=720)
Home in Vacamonte
4.89 out of 5 average rating, 19 reviewsCozy beach house close to town!
![](https://a0.muscache.com/im/pictures/miso/Hosting-652032998451882707/original/bb995226-c2cd-4ee9-9664-29c5743316f3.jpeg?im_w=720)
Home in Panama City
5 out of 5 average rating, 3 reviewsBeautiful 4 bedroom House with Pool!
Weekly house rentals
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Home in Panamá Oeste
5 out of 5 average rating, 6 reviewsSpecious house that can accommodate up to seven
![](https://a0.muscache.com/im/pictures/miso/Hosting-1184739329678601511/original/bb08b093-f42c-4c26-936c-fe963a9cd06a.jpeg?im_w=720)
Home in Panama City
New place to stayHouse next to Ciudad del Saber
![](https://a0.muscache.com/im/pictures/miso/Hosting-1070346870256850841/original/0584fde8-f412-4bbe-977d-4adf5cf93533.jpeg?im_w=720)
Home in Panamá
New place to staySpacious Casa Familiar Aeropuerto
![](https://a0.muscache.com/im/pictures/miso/Hosting-1195770311345918096/original/2cac93ed-a3b7-4020-8806-310a916429b8.jpeg?im_w=720)
Home in Panamá
New place to stayA Beauty Hm#5 Cerro Azul Panama
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Home in Panamá
New place to stayLuxurious cottage Cerro Azul
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Home in Arraiján
New place to stayBeach House in Panama City
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Home in Panamá
Home On The Lake Cerro Azul
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Home in San Miguelito
New place to stayGorgeous 3bed near panama city & airport
Private house rentals
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Home in Panama City
New place to stayCasa Grande - Panama City Centro
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Home in Panamá
Spacious and charming house near canal
![](https://a0.muscache.com/im/pictures/miso/Hosting-1035031202346165606/original/abe7626b-cd4c-487a-9448-bfac83f6fc82.jpeg?im_w=720)
Home in Panamá
Duplex House located in Clayton
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Home in Panamá
New place to stayhouse Villas del Bosque, Panama.
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Home in Panamá
Natural house
![](https://a0.muscache.com/im/pictures/hosting/Hosting-1177713064716405978/original/5516d050-21a1-431b-8db1-0ff2687eabe7.jpeg?im_w=720)
Home in Panamá
New place to stayBrisa's Point Home
![](https://a0.muscache.com/im/pictures/hosting/Hosting-1069857573329153211/original/e309bfed-79fc-4397-b2c1-394a051eb6f1.jpeg?im_w=720)
Home in Panamá
Your Little House in Linda Vista
![](https://a0.muscache.com/im/pictures/miso/Hosting-47094991/original/93010477-b44a-4004-abb9-be32b66d82c1.jpeg?im_w=720)
Home in Panamá
4.33 out of 5 average rating, 15 reviewsCerro Azul - Casa Entera with Private Pool
Quick stats about house rentals in Panama City
Total rentals
420 properties
Nightly prices starting at
$10 before taxes and fees
Total number of reviews
5.1K reviews
Family-friendly rentals
150 properties are a good fit for families
Pet-friendly rentals
130 properties allow pets
Rentals with a pool
90 properties have a pool
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