Guesthouse vacation rentals in Johns Island
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Top-rated guesthouse rentals in Johns Island
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Johns Island guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
Dec 5 – 12
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 220 reviewsGreen Garden Studio @greengardenstudio2017
Sep 26 – Oct 3
Guesthouse in Summerville
4.98 out of 5 average rating, 643 reviews★Delightful guest house near historic plantations★
Apr 6 – 13
Guesthouse in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
Oct 21 – 28
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Nov 25 – Dec 2
Guesthouse in Charleston
4.99 out of 5 average rating, 264 reviewsSpacious Daniel Island Apartment
Oct 8 – 15
Guesthouse in Charleston
4.93 out of 5 average rating, 317 reviewsCozy Island Cottage
Mar 21 – 28
Guesthouse in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
Jan 6 – 13
Guest house rentals with a patio
Guesthouse in Charleston
4.98 out of 5 average rating, 123 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Sep 26 – Oct 3
Guesthouse in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
Apr 21 – 28
Guesthouse in Johns Island
5.0 out of 5 average rating, 55 reviewsDriftwood Cottage
Oct 23 – 30
Guesthouse in Charleston
5.0 out of 5 average rating, 12 reviewsLowcountry Guesthouse
Jul 28 – Aug 2
Guesthouse in Charleston
4.85 out of 5 average rating, 26 reviewsAdorable Studio Apartment with Patio
Jul 28 – Aug 4
Guesthouse in Charleston
5.0 out of 5 average rating, 13 reviewsGas Light Carriage House James Island
Oct 14 – 21
Guesthouse in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
Dec 10 – 17
Guesthouse in Charleston
5.0 out of 5 average rating, 23 reviews1/1 sleeps 3 ADU Modern+Amazing!
Jul 10 – 17
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.98 out of 5 average rating, 244 reviewsDetached Guest Suite
Apr 4 – 11
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 407 reviewsGuesthouse Convenient to Charleston, Shem Creek, and Beaches
Apr 28 – May 5
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 222 reviewsCozy Apartment in Mount Pleasant
Apr 28 – May 5
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 436 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Nov 2 – 9
Guesthouse in Charleston
5.0 out of 5 average rating, 144 reviewsThe Guesthouse at Old Orchard
Oct 22 – 29
Guesthouse in Charleston
4.99 out of 5 average rating, 206 reviewsRedesigned suite! 12min to city, pet-friendly
Sep 30 – Oct 7
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 248 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Aug 26 – Sep 2
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 258 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Jul 15 – 22
Quick stats about guesthouse rentals in Johns Island
Total rentals
40 properties
Wifi availability
40 properties include access to wifi
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Total number of reviews
5.7K reviews
Nightly prices starting at
$40 before taxes and fees
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- Family-friendly rentals Johns Island
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- Rentals with a kayak Johns Island
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- Apartment rentals Johns Island
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