Guesthouse vacation rentals in Greenville

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Top-rated guesthouse rentals in Greenville

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in Greer
CLEAN 1 BD Suite - 1.7 Miles From Downtown Greer
Welcome to our NEW modern detached guesthouse. It features a private entrance with plenty of parking. The kitchen is equipped with a refrigerator, oven, microwave, Beverage station, and Basic kitchen tools. The living room includes a couch that seats 3, a tv, and access to your own private outdoor area. The bedroom features a comfortable queen-size bed and TV. The bathroom has a huge walk-in tiled shower. We're Located 1.7 miles from downtown Greer, so there is always something to do nearby.
Feb 13 – 20
$88 per night
4.96 out of 5 average rating, 249 reviews
Guest favorite
Guesthouse in Greenville
Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.
Jan 6 – 13
$73 per night
4.92 out of 5 average rating, 563 reviews
Guest favorite
Guesthouse in Greenville
The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.
Feb 11 – 18
$102 per night
4.99 out of 5 average rating, 347 reviews

Popular amenities for Greenville guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Greer
Executive Suite on a farm @GSP Airport
Jun 3 – 10
$79 per night
4.96 out of 5 average rating, 232 reviews
Guest favorite
Guesthouse in Fountain Inn
Main Street Guest Cottage
Jun 4 – 11
$72 per night
4.92 out of 5 average rating, 250 reviews
Guest favorite
Guesthouse in Saluda
Carolina Cottage Guest House
Nov 2 – 9
$99 per night
4.98 out of 5 average rating, 250 reviews
Guest favorite
Guesthouse in Tryon
Historic Jockey Cottage, TIEC 20 mins, Tryon 5
Mar 14 – 21
$99 per night
4.97 out of 5 average rating, 102 reviews
Guest favorite
Guesthouse in Simpsonville
Private Suite in Downtown Simpsonville
Jan 2 – 9
$98 per night
4.94 out of 5 average rating, 217 reviews
Guest favorite
Guesthouse in Pendleton
La Bella Farm
Apr 1 – 8
$70 per night
4.9 out of 5 average rating, 238 reviews
Guest favorite
Guesthouse in Flat Rock
The Cottage at the Hopewood Estate Flat Rock, NC
Sep 27 – Oct 4
$170 per night
4.96 out of 5 average rating, 102 reviews
Guest favorite
Guesthouse in Inman
Cozy 1 BR Cottage - Great Location!
Jan 3 – 10
$90 per night
4.97 out of 5 average rating, 36 reviews
Guest favorite
Guesthouse in Travelers Rest
Travelers Rest Country Retreat Two miles to NGU
Jan 30 – Feb 6
$128 per night
5.0 out of 5 average rating, 47 reviews
Guest favorite
Guesthouse in Greenville
Quiet Guest Apartment in the Woods
Feb 14 – 21
$82 per night
4.78 out of 5 average rating, 46 reviews
Guest favorite
Guesthouse in Pelzer
South Oaks Guesthouse
Apr 11 – 18
$99 per night
4.97 out of 5 average rating, 108 reviews
Guest favorite
Guesthouse in Brevard
Studio 84, Brevard NC
Aug 16 – 23
$135 per night
4.97 out of 5 average rating, 98 reviews

Guest house rentals with a patio

Guest favorite
Guesthouse in Tryon
1 bedroom guest house on horse property in Tryon
Dec 14 – 21
$100 per night
4.99 out of 5 average rating, 113 reviews
Guest favorite
Guesthouse in Greenville
Finished Room over Garage (FROG) on Reedy River
Apr 7 – 14
$65 per night
4.98 out of 5 average rating, 60 reviews
Guest favorite
Guesthouse in Fountain Inn
The Woodlands - Spacious Apt in Central Location!
Nov 1 – 8
$66 per night
4.85 out of 5 average rating, 79 reviews
Guest favorite
Guesthouse in Greenville
Tranquil 2BR Guest House on Pond by Furman
Mar 4 – 11
$81 per night
4.92 out of 5 average rating, 25 reviews
Guest favorite
Guesthouse in Mauldin
TICA’S HOME Your cozy Home away from Home
May 25 – Jun 1
$81 per night
4.93 out of 5 average rating, 44 reviews
Guest favorite
Guesthouse in Greenville
Historic Earle Street Guest House
Apr 22 – 29
$92 per night
4.95 out of 5 average rating, 22 reviews
Guest favorite
Guesthouse in Greenville
Chic Studio with Private Deck
Sep 25 – Oct 2
$93 per night
5.0 out of 5 average rating, 19 reviews
Guest favorite
Guesthouse in Greenville
Upscale 1BR pet+ monthly near everything GVL
Jun 14 – 21
$79 per night
5.0 out of 5 average rating, 8 reviews
Guest favorite
Guesthouse in Greenville
Cozy Downtown GVL Studio
Sep 26 – Oct 3
$122 per night
4.93 out of 5 average rating, 56 reviews
Guest favorite
Guesthouse in Inman
Foothills Favorite
Sep 29 – Oct 6
$73 per night
5.0 out of 5 average rating, 85 reviews
Guest favorite
Guesthouse in Piedmont
Shou-Sugi-Ban Retreat on the Saluda River
Oct 2 – 9
$176 per night
4.97 out of 5 average rating, 33 reviews
Guest favorite
Guesthouse in Campobello
Bungalow on a 3 acre mini farm
Aug 9 – 16
$72 per night
4.97 out of 5 average rating, 60 reviews

Guest house rentals with a washer and dryer

Superhost
Guesthouse in Greenville
The Carriage House (pet friendly)
Mar 25 – Apr 1
$82 per night
4.89 out of 5 average rating, 188 reviews
Guest favorite
Guesthouse in Lyman
Blue Heron Hideaway Lakeside Retreat
Aug 16 – 23
$115 per night
4.99 out of 5 average rating, 117 reviews
Guest favorite
Guesthouse in Tryon
Horse Haven - 1 Bedroom Loft 8 Miles to TIEC
Mar 25 – Apr 1
$75 per night
4.95 out of 5 average rating, 142 reviews
Guest favorite
Guesthouse in Greenville
Chic CityFlat-walk to Main St, parking! &pvt patio
Apr 9 – 16
$155 per night
4.97 out of 5 average rating, 232 reviews
Guest favorite
Guesthouse in Greenville
TheArk
May 9 – 16
$73 per night
4.86 out of 5 average rating, 29 reviews
Guest favorite
Guesthouse in Taylors
Entire Cottage with Hot Tub!
Jun 7 – 14
$92 per night
5.0 out of 5 average rating, 26 reviews
Guest favorite
Guesthouse in Pelzer
Quaint guest cottage in Upstate
Sep 5 – 12
$90 per night
4.9 out of 5 average rating, 20 reviews
Guest favorite
Guesthouse in Travelers Rest
Rest Your Caboose Cottage
May 6 – 13
$189 per night
5.0 out of 5 average rating, 11 reviews
Guest favorite
Guesthouse in Taylors
The oaks cottage
Jun 8 – 15
$129 per night
4.94 out of 5 average rating, 31 reviews
Guest favorite
Guesthouse in Greenville
The Spring Valley Retreat
Jul 20 – 27
$134 per night
4.99 out of 5 average rating, 74 reviews
Guest favorite
Guesthouse in Brevard
Luxury Cottage, Estate Property, Walk to Downtown
Oct 7 – 14
$202 per night
5.0 out of 5 average rating, 14 reviews
Superhost
Guesthouse in Greenville
Mod studio- loft, outdoor covered space & parking
Aug 11 – 18
$143 per night
4.97 out of 5 average rating, 32 reviews

Quick stats about guesthouse rentals in Greenville

Total rentals

20 properties

Popular amenities

Kitchen, Wifi, and Pool

Wifi availability

20 properties include access to wifi

Rentals with dedicated workspaces

10 properties have a dedicated workspace

Total number of reviews

2.4K reviews

Nightly prices starting at

$50 before taxes and fees

Destinations to explore