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Guesthouse vacation rentals in Greenville County

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Top-rated guesthouse rentals in Greenville County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in Greenville
Historic 19th Century Cabin/Guest House
This 19th century cabin is your perfect cozy getaway. This guest house is located on a 3.5 acre property, secluded from the historic neighborhood, though it's just 3 miles from downtown Greenville and the Bon Secours Wellness Arena. Less than a mile to the Swamp Rabbit Trail, this cottage is perfect for jaunts to downtown Greenville, Furman University, Paris Mountain, Travelers Rest and Unity Park! Micro weddings and events are available upon request and approval with applicable fees applied.
Nov 2 – 9
$78 per night
Guest favorite
Guesthouse in Greenville
The Cottage at Old Oaks Farm
Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.
Feb 5 – 12
$102 per night
Guest favorite
Guesthouse in Greenville
Greenville With A View!
ONLY 10-15 MINUTE DRIVE TO THE HEART OF BEAUTIFUL DOWNTOWN GREENVILLE! We are only 11 miles to GSP Airport; 6 miles to Greenville Downtown Airport; and 10 minutes to the Swamp Rabbit Trail. We are minutes to Furman University, Bob Jones University, North Greenville University and Clemson University is only 45 minutes away. We are tucked away open top of Paris Mountain. If you want to bike, hike, paddle, swim, boat or just soak it all in, start here!
Jul 14 – 21
$120 per night

Popular amenities for Greenville County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Pendleton
La Bella Farm
Apr 24 – May 1
$69 per night
Guest favorite
Guesthouse in Simpsonville
Private Suite in Downtown Simpsonville
Jun 30 – Jul 7
$107 per night
Guest favorite
Guesthouse in Fountain Inn
Main Street Guest Cottage
Jun 9 – 16
$72 per night
Guest favorite
Guesthouse in Greer
Executive Suite on a farm @GSP Airport
Dec 16 – 23
$127 per night
Guest favorite
Guesthouse in Tryon
Historic Jockey Cottage, TIEC 20 mins, Tryon 5
Jan 5 – 12
$105 per night
Guest favorite
Guesthouse in Travelers Rest
Travelers Rest Country Retreat Two miles to NGU
Oct 25 – Nov 1
$128 per night
Guest favorite
Guesthouse in Greenville
Quiet Guest Apartment in the Woods
Nov 1 – 8
$82 per night
Guest favorite
Guesthouse in Pelzer
South Oaks Guesthouse
Dec 7 – 14
$99 per night

Guest house rentals with a patio

Guest favorite
Guesthouse in Tryon
1 bedroom guest house on horse property in Tryon
Dec 8 – 15
$100 per night
Guest favorite
Guesthouse in Greenville
Finished Room over Garage (FROG) on Reedy River
Apr 21 – 28
$65 per night
Guest favorite
Guesthouse in Fountain Inn
The Woodlands - Spacious Apt in Central Location!
Jan 10 – 17
$66 per night
Guest favorite
Guesthouse in Greenville
Tranquil 2BR Guest House on Pond by Furman
Jul 30 – Aug 6
$93 per night
Guest favorite
Guesthouse in Greenville
Chic Studio with Private Deck
Apr 10 – 17
$93 per night
Guest favorite
Guesthouse in Campobello
Bungalow on a 3 acre mini farm
Sep 21 – 28
$72 per night
Guest favorite
Guesthouse in Mauldin
TICA’S HOME Your cozy Home away from Home
Jan 21 – 28
$81 per night
Guest favorite
Guesthouse in Greenville
Historic Earle Street Guest House
Apr 22 – 29
$92 per night
Guest favorite
Guesthouse in Greenville
Upscale 1BR pet+ monthly near everything GVL
May 24 – 31
$79 per night
Guest favorite
Guesthouse in Greenville
Cozy Downtown GVL Studio
Nov 6 – 13
$122 per night
Guest favorite
Guesthouse in Piedmont
Shou-Sugi-Ban Retreat on the Saluda River
Jun 12 – 19
$176 per night
Guest favorite
Guesthouse in Zirconia
Studio Guesthouse in Zirconia
Sep 18 – 25
$108 per night

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Lyman
Blue Heron Hideaway Lakeside Retreat
Aug 9 – 16
$117 per night
Guest favorite
Guesthouse in Greenville
TheArk
May 12 – 19
$73 per night
Guest favorite
Guesthouse in Pelzer
Quaint guest cottage in Upstate
Apr 5 – 12
$97 per night
Guest favorite
Guesthouse in Taylors
Entire Cottage with Hot Tub!
Jun 7 – 14
$87 per night
Guest favorite
Guesthouse in Travelers Rest
Rest Your Caboose Cottage
Jul 20 – 27
$184 per night
Superhost
Guesthouse in Greenville
Mod studio- loft, outdoor covered space & parking
Sep 16 – 23
$160 per night
Guest favorite
Guesthouse in Taylors
The oaks cottage
May 12 – 19
$87 per night
Guest favorite
Guesthouse in Greenville
The Spring Valley Retreat
Sep 27 – Oct 4
$137 per night
Guest favorite
Guesthouse in Fountain Inn
Upscale cottage in Downtown Fountain Inn
May 16 – 23
$93 per night
Guest favorite
Guesthouse in Taylors
Just off Main near Taylors Mill - Clean & Comfy
Apr 19 – 26
$124 per night
Guest favorite
Guesthouse in Travelers Rest
Modern guesthouse in downtown TR
Jul 13 – 20
$115 per night
Guest favorite
Guesthouse in Travelers Rest
Cozy Studio Apartment, Free Parking & Washer/Dryer
Jul 23 – 30
$98 per night

Destinations to explore