House vacation rentals in Greenville County

Find and book unique houses on Airbnb

Top-rated house rentals in Greenville County

Guests agree: these houses are highly rated for location, cleanliness, and more.

Guest favorite
Home in Greenville
A Tranquil Place (near downtown Greenville)
A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!
Mar 13 – 20
$84 per night
4.97 out of 5 average rating, 145 reviews
Guest favorite
Home in Greenville
Maplewood Cottage at Saluda River Farms
This cozy 400sqft space is perfect for a weekend getaway. It has everything you need to enjoy a short get away. Saluda River Farms is an 8 acre farm on the Saluda River. Bring your Kayaks to enjoy a relaxing trip up the river or ride your bike on the beautiful back country roads. We are located 7 miles from DT Greenville and only 20 minutes from nature hikes and quaint little country towns. You can also relax on the farm - we have 3 goats and 6 chickens. Pets are always welcome.
Jun 5 – 12
$74 per night
4.9 out of 5 average rating, 102 reviews
Guest favorite
Home in Greenville
Cozy 2Br Near the Zoo and Swamp Rabbit Trail
Cozy 2 bedroom home in Greenville. Bright living room when you first walk in featuring a smart tv . Two bedrooms, both with queen size beds. Updated kitchen with full size stove, refrigerator, and dishwasher. Washer and dryer closet off of kitchen also on site. No dining room, however, a small bar table with two bar stools. Small covered back deck for relaxing. Located in an older neighborhood, very convenient to the swamp rabbit trail, the Greenville Zoo, and Cleveland Park.
Mar 4 – 11
$76 per night
4.98 out of 5 average rating, 101 reviews

Popular amenities for Greenville County house rentals

House rentals with a pool

Guest favorite
Home in Greenville
Saluda Splash Home
Aug 1 – 8
$161 per night
4.88 out of 5 average rating, 112 reviews
Guest favorite
Home in Greenville
Palmetto Escape - Pool- 6.6 mi DTWN GVL-Firepit
Sep 30 – Oct 7
$264 per night
5.0 out of 5 average rating, 102 reviews
Superhost
Home in Greer
Shalom House - walkable to DT Greer SC
Aug 15 – 22
$109 per night
4.81 out of 5 average rating, 128 reviews
Guest favorite
Home in Greenville
Southern Bungalow with Stock Tank Pool + Firepit
Sep 16 – 23
$153 per night
4.92 out of 5 average rating, 100 reviews
Guest favorite
Home in Campobello
Hot Tub Game Room Cozy Family Getaway
Oct 31 – Nov 7
$214 per night
4.97 out of 5 average rating, 193 reviews
Guest favorite
Home in Greenville
Lux Home w/Pool Gym Private Entrance and more!
Oct 13 – 20
$500 per night
5.0 out of 5 average rating, 6 reviews
Guest favorite
Home in Greenville
Pet-Friendly 4BR: Pool, Screen Porch, Fenced Yard
Mar 20 – 27
$228 per night
4.98 out of 5 average rating, 46 reviews
Guest favorite
Home in Greenville
NEW! FAMILY FRIENDLY GREENVILLE VACATION HOME
Nov 24 – Dec 1
$185 per night
5.0 out of 5 average rating, 19 reviews
Guest favorite
Home in Greenville
Walk to Furman & Swamp Rabbit! BBQ & Jetted Tub
Jul 6 – 13
$424 per night
5.0 out of 5 average rating, 11 reviews
Guest favorite
Home in Greer
NEW - Heated Pool - Hot Tub - Game Room - Sauna -
Nov 11 – 18
$486 per night
5.0 out of 5 average rating, 49 reviews
Guest favorite
Home in Transylvania County
*NEW* Modern Mountain Retreat - Golf-Pickleball-La
Aug 16 – 23
$233 per night
5.0 out of 5 average rating, 10 reviews
Guest favorite
Home in Powdersville
Charming 5 Bedroom Family-Friendly Spacious Home
May 13 – 20
$210 per night
4.92 out of 5 average rating, 12 reviews

Weekly house rentals

Guest favorite
Home in Greenville
Paris Mtn. Loft Home - State Park Pass Included
Dec 9 – 16
$125 per night
4.97 out of 5 average rating, 273 reviews
Guest favorite
Home in Easley
Home-Run on Nalley Street, Easley SC Unit A
Aug 14 – 21
$96 per night
4.9 out of 5 average rating, 107 reviews
Guest favorite
Home in Greenville
Burrow Boutique studio -fast EV plug /fire pit
Aug 12 – 19
$131 per night
4.92 out of 5 average rating, 365 reviews
Guest favorite
Home in Greenville
Cottage Haven- King bd, Clean, 2.2 mi to downtown!
Oct 15 – 22
$115 per night
4.96 out of 5 average rating, 215 reviews
Guest favorite
Home in Greenville
Lavinia House
Nov 9 – 16
$257 per night
4.99 out of 5 average rating, 285 reviews
Guest favorite
Home in Greenville
2 Living Spaces -2800 ft.²- Sleeps 10
Aug 24 – 31
$188 per night
4.99 out of 5 average rating, 123 reviews
Guest favorite
Home in Easley
Large lake house - 15 min to Downtown Greenville
Dec 8 – 15
$497 per night
4.92 out of 5 average rating, 131 reviews
Guest favorite
Home in Greenville
Stunning Modern Home w/ Firepit~ Close to Downtown
May 30 – Jun 6
$240 per night
4.94 out of 5 average rating, 124 reviews
Guest favorite
Home in Travelers Rest
The Enoree at Travelers Rest- Between Furman & NGU
Jul 9 – 16
$97 per night
4.9 out of 5 average rating, 224 reviews
Superhost
Home in Greenville
Beautiful Downtown 4BD/2.5BA - Greenville, SC
Oct 7 – 14
$249 per night
4.89 out of 5 average rating, 116 reviews
Guest favorite
Home in Greenville
Ultra Luxury Downtown House, Voted GVL's #1 AirBnb
Feb 17 – 24
$206 per night
4.98 out of 5 average rating, 423 reviews
Guest favorite
Home in Greenville
Spectacular home 1 mile from Main St Greenville!
May 21 – 28
$132 per night
4.96 out of 5 average rating, 125 reviews

Private house rentals

Guest favorite
Home in Greenville
⭐️ Comfy Eastside Home Close to Downtown ⭐️
May 21 – 28
$114 per night
4.86 out of 5 average rating, 207 reviews
Guest favorite
Home in Travelers Rest
Claire's tearoom / artist suite
Sep 28 – Oct 5
$65 per night
4.85 out of 5 average rating, 534 reviews
Guest favorite
Home in Greenville
Cozy Bricks Great Back Deck & Yard
Aug 1 – 8
$111 per night
4.94 out of 5 average rating, 100 reviews
Guest favorite
Home in Pickens
Hidden Retreat
Oct 5 – 12
$84 per night
4.98 out of 5 average rating, 137 reviews
Guest favorite
Home in Easley
Spectacular Lakefront Retreat on the Saluda
May 29 – Jun 5
$200 per night
4.91 out of 5 average rating, 175 reviews
Guest favorite
Home in Greenville
3BR/2Ba, soaker tub, 5 min to downtown: Crescent
Sep 9 – 16
$208 per night
4.95 out of 5 average rating, 182 reviews
Guest favorite
Home in Greenville
Cozy, Family Friendly Upstate Retreat w/ Firepit
Apr 23 – 30
$166 per night
4.88 out of 5 average rating, 230 reviews
Guest favorite
Home in Greenville
Plumfield
Jun 14 – 21
$139 per night
4.97 out of 5 average rating, 151 reviews
Guest favorite
Home in Greenville
"Grandma's Farmhouse" by Greenville DWTN/ Hospital
Apr 16 – 23
$93 per night
4.87 out of 5 average rating, 165 reviews
Guest favorite
Home in Greenville
Rustic Retreat: Cozy Getaway
May 4 – 11
$73 per night
5.0 out of 5 average rating, 12 reviews
Superhost
Home in Greenville
Greenville Modern Retreat - 8 minutes to Downtown
Dec 9 – 16
$86 per night
4.92 out of 5 average rating, 25 reviews
Guest favorite
Home in Greenville
2BR with Beautiful Fenced in Yard
Jan 12 – 19
$71 per night
5.0 out of 5 average rating, 8 reviews

Destinations to explore