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House vacation rentals in Los Santos Province
Find and book unique houses on Airbnb
Top-rated house rentals in Los Santos Province
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Los Santos Province house rentals
House rentals with a pool
![](https://a0.muscache.com/im/pictures/miso/Hosting-46145074/original/875cee9f-d2cd-4a66-9a4d-e77f5247cfcc.jpeg?im_w=720)
Home in Cambutal
4.67 out of 5 average rating, 6 reviewsCasa Gerard
![](https://a0.muscache.com/im/pictures/miso/Hosting-959627924334674289/original/0bc67e0d-ef43-4924-94e1-f3ef4d3f42fe.jpeg?im_w=720)
Home in Playa Venao
5 out of 5 average rating, 5 reviewsComeSurf! 3b+2b Casa Palma 3 Walk to the Beach
![](https://a0.muscache.com/im/pictures/miso/Hosting-974061333836672456/original/c81c64d3-26a5-47a6-940d-85116ab6f9a4.jpeg?im_w=720)
Home in Pedasi
Casa Del Amor in Pedasi Panama
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Home in Las Escobas del Venado
Vila Sueño Azul - Blue Venao 3BR
![](https://a0.muscache.com/im/pictures/miso/Hosting-865931352157063921/original/708f6ddc-a348-4bb9-8e2a-fa6c205f96be.jpeg?im_w=720)
Home in Pedasí
Condo Villa Loft Colonial
![](https://a0.muscache.com/im/pictures/miso/Hosting-4886283/original/074f54d1-30d6-4d53-8de3-d50ba934ea2a.jpeg?im_w=720)
Home in Playa Venao
4.9 out of 5 average rating, 117 reviewsBeautiful Home Directly on Playa Venao Sleeps 8-10
![](https://a0.muscache.com/im/pictures/miso/Hosting-1135117716580762064/original/461ae4ca-69f6-43f3-81f5-2fd83bac5f2f.jpeg?im_w=720)
Home in Pedasi
5 out of 5 average rating, 4 reviewsA minimalist Casita in Pedasi
![](https://a0.muscache.com/im/pictures/0a0ea404-95d7-42fe-9b2e-13fe5830333d.jpg?im_w=720)
Home in PA
4.83 out of 5 average rating, 42 reviewsCozy and quiet beach house- pool
Weekly house rentals
![](https://a0.muscache.com/im/pictures/miso/Hosting-29882093/original/c91393f5-6589-4124-be46-d2f271276c27.jpeg?im_w=720)
Home in Pedasí
4.73 out of 5 average rating, 30 reviewsVillage House #1 - 2BR Beautiful Towny Pedasi Home
![](https://a0.muscache.com/im/pictures/miso/Hosting-904233597058170209/original/4e54afe1-64e2-4e98-bbf4-af6940fa2969.jpeg?im_w=720)
Home in Las Tablas
4.67 out of 5 average rating, 3 reviewsVilla Carola, Las Tablas
![](https://a0.muscache.com/im/pictures/efec2608-a399-40ac-978c-0d965a620a60.jpg?im_w=720)
Home in Chitré
4.88 out of 5 average rating, 8 reviewsMinimalist House In Chitre
![](https://a0.muscache.com/im/pictures/miso/Hosting-790738195106581844/original/bbf11b48-5ad3-49ea-9f6c-821b3a5d13ea.jpeg?im_w=720)
Home in Chitre
4.64 out of 5 average rating, 22 reviewsCozy and downtown Casa
![](https://a0.muscache.com/im/pictures/hosting/Hosting-1055964984335959341/original/04767f36-3794-4725-a98c-faed03dd6331.jpeg?im_w=720)
Home in Monagrillo
5 out of 5 average rating, 3 reviewsSan Juan Bautista, Herrera
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Home in Los Ángeles
5 out of 5 average rating, 3 reviewsLa casa de Campo de guelo Nino
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Home in Chitré
4.63 out of 5 average rating, 8 reviewsCozy country house.
![](https://a0.muscache.com/im/pictures/miso/Hosting-1069090293589372383/original/f35a8812-14ab-49f8-aa15-f157fea3b114.jpeg?im_w=720)
Home in Chitre
4.67 out of 5 average rating, 3 reviewsCasa Abuela Aurelia
Private house rentals
![](https://a0.muscache.com/im/pictures/8f874911-54da-4efb-b281-166fc4745582.jpg?im_w=720)
Home in Las Tablas
4.8 out of 5 average rating, 5 reviewsLa casita de Cuca
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Home in La Villa de Los Santos
New place to stayHouse in the Villa of Los Santos.
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Home in Playa Venao
New place to stayCasa Mariposa - Playa Venao
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Home in Las Escobas del Venado
New place to stayBlue Venao Sea Breeze Sanctuary/ Villa 32
![](https://a0.muscache.com/im/pictures/miso/Hosting-1107235075536618069/original/f2daae99-3f79-48b4-bf25-a583429f04eb.jpeg?im_w=720)
Home in Playa Venao
Family Haven 3-Bedroom Retreat @BlueVenao
![](https://a0.muscache.com/im/pictures/miso/Hosting-1094898597556281399/original/f4e32704-adc5-4da6-bbea-1f958364f0d6.jpeg?im_w=720)
Home in Playa Venao
Casa Inita - Couple's Getaway
![](https://a0.muscache.com/im/pictures/hosting/Hosting-1158034271888422209/original/1a4fb922-e3a9-46f6-895c-362e514e5303.jpeg?im_w=720)
Home in La Villa de Los Santos
New place to stayVilla Cristina
![](https://a0.muscache.com/im/pictures/miso/Hosting-794768786046989657/original/f288a0ab-14ed-4d8c-b3cc-17b49343937b.jpeg?im_w=720)
Home in Pedasi
Luxurious Friends & Family Escape |Oceanfront Pool
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