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Guesthouse vacation rentals in Lexington County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Lexington County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Lexington County guesthouse rentals
Family-friendly guest house rentals
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Guesthouse in Columbia
4.87 out of 5 average rating, 90 reviewsCozy Camper in St. Andrews, Irmo, Harbison Blvd.
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Guesthouse in Columbia
4.08 out of 5 average rating, 39 reviewsCoziest Studio Cabin near USC, 5 pts & Hospitals
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Guesthouse in Columbia
5 out of 5 average rating, 382 reviewsCozy studio apartment, convenient location
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Guesthouse in West Columbia
4.95 out of 5 average rating, 620 reviewsCarriage House: Studio Bed & Bath - Pool & Hot Tub
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Guesthouse in Lexington
4.94 out of 5 average rating, 252 reviewsCome Pause and Relax!
Guest house rentals with a patio
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Guesthouse in Lexington
5 out of 5 average rating, 51 reviewsA Pondside Oasis close to Lake Murray and Columbia
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Guesthouse in Columbia
5 out of 5 average rating, 75 reviewsRestful Refuge
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Guesthouse in Lexington County
5 out of 5 average rating, 16 reviewsBoat House
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Guesthouse in Lexington County
4.96 out of 5 average rating, 28 reviewsMom's Place
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Guesthouse in Columbia
4.91 out of 5 average rating, 34 reviewsThe Wren | 1BR 2BA Guesthouse
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Guesthouse in Columbia
5 out of 5 average rating, 6 reviewsThe Carriage House @Downtown!
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Guesthouse in Chapin
4.96 out of 5 average rating, 24 reviewsNEW Lakefront guesthouse with private dock.
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Guesthouse in Batesburg-Leesville
5 out of 5 average rating, 6 reviewsBeautiful Lake Front 1 bedroom Guest House
Guest house rentals with a washer and dryer
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Guesthouse in Columbia
4.89 out of 5 average rating, 374 reviewsCozy retreat near Williams Brice/Ft. Jackson/UofSC
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Guesthouse in Lexington
5 out of 5 average rating, 8 reviewsGarage Apartment
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Guesthouse in West Columbia
4.96 out of 5 average rating, 50 reviewsSpringdale Getaway
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Guesthouse in Columbia
4.94 out of 5 average rating, 32 reviewsCasa Abelia - Downtown Columbia
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Guesthouse in Columbia
4.89 out of 5 average rating, 66 reviewsFaber's Rest LLC
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Guesthouse in Columbia
5 out of 5 average rating, 13 reviewsTrendy 1 Bed/1 Bath in quiet upscale neighborhood
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Guesthouse in Columbia
New place to stayFull Kitchen, Wi-Fi, TV, W/D
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Guesthouse in Columbia
4.76 out of 5 average rating, 78 reviewsEarlewood Craftsman - Guest House LONG TERM STAYS
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