Guesthouse vacation rentals in National City
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in National City
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for National City guesthouse rentals
Family-friendly guest house rentals
Guesthouse in La Mesa
4.99 out of 5 average rating, 247 reviewsSpacious, private Mt. Helix country style studio
Apr 28 – May 5
Guesthouse in San Diego
4.97 out of 5 average rating, 508 reviewsCentral & Serene Secret Garden Guesthouse
Sep 2 – 9
Guesthouse in La Mesa
4.92 out of 5 average rating, 208 reviewsFig Tree Bungalow
Oct 6 – 13
Guesthouse in San Diego
4.99 out of 5 average rating, 364 reviews*Private Canyon Retreat: Your Own Guesthouse*
Dec 3 – 10
Guesthouse in San Diego
4.93 out of 5 average rating, 449 reviewsPrivate Cottage in Walkable North Park w/AC
Jun 3 – 10
Guesthouse in San Diego
4.91 out of 5 average rating, 356 reviewsLa Casita - Fully Updated Casita in Mission Hills
Oct 19 – 26
Guesthouse in San Diego
4.94 out of 5 average rating, 333 reviewsThe BEST NEST Clean, peaceful, private, affordable
Jan 11 – 18
Guesthouse in San Diego
4.81 out of 5 average rating, 432 reviewsStudio in the Heart of South Park!
Jan 16 – 23
Guest house rentals with a patio
Guesthouse in San Diego
4.96 out of 5 average rating, 104 reviewsCozy Urban Casita! Near Zoo, Gaslamp and Coronado
May 17 – 24
Guesthouse in La Mesa
4.98 out of 5 average rating, 251 reviewsLa Mesa Suite
Apr 15 – 22
Guesthouse in San Diego
4.93 out of 5 average rating, 122 reviewsModern Guest House with pool, steps to SDSU
Sep 5 – 12
Guesthouse in La Mesa
4.97 out of 5 average rating, 130 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Sep 20 – 27
Guesthouse in San Diego
4.98 out of 5 average rating, 125 reviewsPrivate Studio Cottage with Outdoor Patio
Dec 19 – 26
Guesthouse in San Diego
4.91 out of 5 average rating, 151 reviewsCentral studio w/ private outdoor space & parking
Dec 14 – 21
Guesthouse in San Diego
4.99 out of 5 average rating, 143 reviewsMission Hills-Entire Guest House-Center of it All
Jul 28 – Aug 2
Guesthouse in Lakeside
4.94 out of 5 average rating, 100 reviewsSky Mesa-Adorable Cottage on the Hill
Apr 28 – May 5
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.95 out of 5 average rating, 295 reviews*BEAUTIFUL* Sunny Home in Golden Hill
Jul 28 – Aug 2
Guesthouse in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
Sep 16 – 23
Guesthouse in San Diego
4.97 out of 5 average rating, 306 reviewsPrivate Guesthouse in Trendy North Park
Jun 8 – 15
Guesthouse in La Mesa
5.0 out of 5 average rating, 244 reviewsHawks nest
Jun 14 – 21
Guesthouse in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
Sep 16 – 23
Guesthouse in San Diego
4.98 out of 5 average rating, 118 reviewsCasita Hermosa - Close to everything in San Diego
Oct 22 – 29
Guesthouse in San Diego
4.87 out of 5 average rating, 418 reviewsThe Golden Hill mosaic "casita"
Jul 7 – 12
Guesthouse in San Diego
4.98 out of 5 average rating, 205 reviewsOur Garden Cottage: A home away from home.
Nov 16 – 23
Quick stats about guesthouse rentals in National City
Total rentals
40 properties
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
2.6K reviews
Nightly prices starting at
$50 before taxes and fees
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