Guesthouse vacation rentals in San Diego County

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Top-rated guesthouse rentals in San Diego County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in San Diego
Tropical on Texas
Private casita (studio) with kitchenette, day bed with trundle so easily can accommodate two singles or can become a king size bed. Very near zoo, shopping, restaurants, stadium, minutes from Sea World, downtown, convention center, Gaslamp, airport, beaches/bay. Immediate freeway access, 5 minutes to trolley, bus stop at corner. Great walk-ability. If you would like a taste of paradise & central location we look forward to your visit. Please no extra guests they may come to visit but not stay.
Mar 13 – 20
$91 per night
4.99 out of 5 average rating, 181 reviews
Guest favorite
Guesthouse in Encinitas
Coastal Farm Sanctuary Stay. 20 min to the Beach.
Coastal Farm Sanctuary guest house, superbly finished. 20 min to beach. Quiet relaxing farm sanctuary retreat. Close to the beach, shops and restaurants. Our location offers an air of tranquility and peace, allowing you to unplug and unwind. There is a full kitchen, space for lounging, an elegant bathroom and a comfortable king sized bed with lush linens. The apartment has a modern country vibe, situated on 2.5 acre estate with privacy and breath-taking views. Please no pets and no smoking.
Feb 19 – 26
$148 per night
4.99 out of 5 average rating, 146 reviews
Guest favorite
Guesthouse in Encinitas
The Tiki Lounge, Leucadia, California
The Lounge is a quaint, cozy 400 sq. ft. one-bedroom detached guesthouse with lots of character in the "funky" community of Leucadia. Located just east of historic Highway 101 in a quiet neighborhood a mile from beach access, you're close to many eclectic shops, restaurants and entertainment. You'll also have access to a semi-private patio and shared access to our back yard, where, as of June 2023, Debe works 3 to 4 days a week in her studio. We really love it here and think you will too.
May 22 – 29
$117 per night
4.98 out of 5 average rating, 122 reviews

Popular amenities for San Diego County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Oceanside
The Flying Mermaid
$103 per night
4.98 out of 5 average rating, 482 reviews
Guest favorite
Guesthouse in Bonita
Garden Cottage with a bathroom, Kitchenet & patio
Jul 15 – 22
$83 per night
4.93 out of 5 average rating, 296 reviews
Guest favorite
Guesthouse in San Diego
Studio in the Heart of South Park!
Dec 9 – 16
$79 per night
4.8 out of 5 average rating, 420 reviews
Guest favorite
Guesthouse in San Diego
Romantic Private Garden Studio Near Downtown
Feb 3 – 10
$102 per night
4.95 out of 5 average rating, 463 reviews
Guest favorite
Guesthouse in La Mesa
Fig Tree Bungalow
May 18 – 25
$105 per night
4.92 out of 5 average rating, 204 reviews
Guest favorite
Guesthouse in Encinitas
Coastal Studio Guesthouse
Nov 2 – 9
$165 per night
4.99 out of 5 average rating, 376 reviews
Guest favorite
Guesthouse in San Diego
North Park, San Diego's Best At Your Doorstep
Apr 19 – 26
$135 per night
4.96 out of 5 average rating, 205 reviews
Guest favorite
Guesthouse in Chula Vista
Private Casita in Great Eastlake Neighborhood
May 17 – 24
$86 per night
4.95 out of 5 average rating, 465 reviews
Guest favorite
Guesthouse in San Diego
Your Kensington Bungalow
Aug 18 – 25
$118 per night
4.96 out of 5 average rating, 245 reviews
Guest favorite
Guesthouse in Encinitas
Cardiff by the Sea Beach Bungalow
Oct 20 – 27
$160 per night
4.96 out of 5 average rating, 339 reviews
Guest favorite
Guesthouse in San Diego
Private Cottage in Walkable North Park w/AC
May 5 – 12
$105 per night
4.93 out of 5 average rating, 439 reviews
Guest favorite
Guesthouse in Dulzura
Vineyard & Winery Guest House
Oct 31 – Nov 7
$102 per night
4.97 out of 5 average rating, 575 reviews

Guest house rentals with a patio

Guest favorite
Guesthouse in La Mesa
La Mesa Suite
Dec 18 – 25
$143 per night
4.97 out of 5 average rating, 237 reviews
Guest favorite
Guesthouse in San Diego
Central studio w/ private outdoor space & parking
Jan 6 – 13
$119 per night
4.93 out of 5 average rating, 135 reviews
Guest favorite
Guesthouse in San Diego
Private Studio Cottage with Outdoor Patio
Oct 23 – 30
$150 per night
4.98 out of 5 average rating, 112 reviews
Guest favorite
Guesthouse in La Mesa
Da Hui Hut-Beachy home/La Mesa’s best view and spa
Jun 9 – 16
$161 per night
4.98 out of 5 average rating, 120 reviews
Guest favorite
Guesthouse in Fallbrook
Fallbrook Treehouse on quiet Bluff. Wifi & Parking
May 1 – 8
$82 per night
4.89 out of 5 average rating, 187 reviews
Guest favorite
Guesthouse in Poway
⭐️Garden studio guesthouse, resort living with pool
May 14 – 21
$140 per night
4.99 out of 5 average rating, 113 reviews
Guest favorite
Guesthouse in San Diego
Modern Guest House with pool, steps to SDSU
Aug 3 – 10
$104 per night
4.92 out of 5 average rating, 113 reviews
Guest favorite
Guesthouse in San Diego
Private, beautiful 1-bedroom 2 story guest house
Apr 18 – 25
$92 per night
4.85 out of 5 average rating, 119 reviews
Guest favorite
Guesthouse in La Mesa
SDCannaBnB #1 *420 *parking *dog-friendly *hot tub
May 23 – 30
$129 per night
4.99 out of 5 average rating, 151 reviews
Guest favorite
Guesthouse in San Diego
Mission Hills-Entire Guest House-Center of it All
Apr 19 – 26
$104 per night
4.98 out of 5 average rating, 127 reviews
Guest favorite
Guesthouse in La Mesa
San Diego Newly Built Private Guesthouse (Sleep 5)
Dec 11 – 18
$121 per night
4.97 out of 5 average rating, 111 reviews
Guest favorite
Guesthouse in Julian
Cozy Country Cottage
Oct 1 – 8
$104 per night
4.95 out of 5 average rating, 213 reviews

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in San Diego
Our Garden Cottage: A home away from home.
Nov 22 – 29
$81 per night
4.99 out of 5 average rating, 203 reviews
Guest favorite
Guesthouse in San Diego
Charming Granny Flat Near SDSU & Transit Center
Apr 11 – 18
$90 per night
4.91 out of 5 average rating, 110 reviews
Guest favorite
Guesthouse in San Diego
Private beach guesthouse w/ private parking
Aug 14 – 21
$125 per night
4.95 out of 5 average rating, 196 reviews
Guest favorite
Guesthouse in San Diego
Waterhaven - A Pondside Oasis
Jan 11 – 18
$195 per night
5.0 out of 5 average rating, 451 reviews
Guest favorite
Guesthouse in San Diego
Cozy guest studio with private deck
Oct 24 – 31
$86 per night
4.9 out of 5 average rating, 720 reviews
Guest favorite
Guesthouse in San Diego
Casita Hermosa - Close to everything in San Diego
May 3 – 10
$155 per night
4.99 out of 5 average rating, 112 reviews
Guest favorite
Guesthouse in San Diego
*BEAUTIFUL* Sunny Home in Golden Hill
May 26 – Jun 2
$124 per night
4.95 out of 5 average rating, 283 reviews
Guest favorite
Guesthouse in La Mesa
Hawks nest
Aug 10 – 17
$157 per night
5.0 out of 5 average rating, 239 reviews
Guest favorite
Guesthouse in San Diego
Carrie’s North Park Casita, in Heart of San Diego
Jul 9 – 16
$135 per night
4.99 out of 5 average rating, 127 reviews
Guest favorite
Guesthouse in El Cajon
Modern mountain guest house. Incredible views
Dec 12 – 19
$153 per night
5.0 out of 5 average rating, 145 reviews
Guest favorite
Guesthouse in Alpine
La Casita Private Resort Spa and Mini Golf Course
May 6 – 13
$160 per night
4.98 out of 5 average rating, 305 reviews
Guest favorite
Guesthouse in San Diego
Relaxing Oasis - short walk to shops & recreation
Jun 29 – Jul 6
$114 per night
4.91 out of 5 average rating, 149 reviews

Destinations to explore