Guesthouse vacation rentals in La Mesa
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Top-rated guesthouse rentals in La Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa guesthouse rentals
Family-friendly guest house rentals
Guesthouse in La Mesa
4.66 out of 5 average rating, 159 reviews(1) Downstair Apartment La Mesa, Mt Helix Area
Guesthouse in Chula Vista
4.95 out of 5 average rating, 482 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in San Diego
4.99 out of 5 average rating, 366 reviews*Private Canyon Retreat: Your Own Guesthouse*
Guesthouse in San Diego
4.97 out of 5 average rating, 513 reviewsCentral & Serene Secret Garden Guesthouse
Guesthouse in San Diego
4.97 out of 5 average rating, 298 reviewsPrivate Guest House with a View
Guesthouse in San Diego
4.94 out of 5 average rating, 336 reviewsThe BEST NEST Clean, peaceful, private, affordable
Guesthouse in San Diego
4.92 out of 5 average rating, 246 reviewsNorth Park Garden Studio
Guesthouse in San Diego
4.98 out of 5 average rating, 160 reviewsNew Guest House - North Park
Guest house rentals with a patio
Guesthouse in San Diego
4.99 out of 5 average rating, 114 reviewsModern Guest House with Patio, Parking, & Laundry
Guesthouse in Lakeside
4.94 out of 5 average rating, 105 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in San Diego
4.98 out of 5 average rating, 107 reviewsStunning Patio! King Bed, Walkable, Games, Parking
Guesthouse in La Mesa
4.84 out of 5 average rating, 124 reviewsPrivate Studio with Panoramic View
Guesthouse in Spring Valley
4.97 out of 5 average rating, 116 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
Guesthouse in National City
4.96 out of 5 average rating, 105 reviewsTrendy 1 BR Guesthouse. Great views, no chores.
Guesthouse in San Diego
4.93 out of 5 average rating, 126 reviewsModern Guest House with pool, steps to SDSU
Guesthouse in San Diego
4.92 out of 5 average rating, 155 reviewsCentral studio w/ private outdoor space & parking
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.96 out of 5 average rating, 112 reviewsRelax in a Centrally Located, Modern Guest House
Guesthouse in La Mesa
4.92 out of 5 average rating, 257 reviewsPrivate Detached Modern Studio located in La Mesa
Guesthouse in San Diego
4.91 out of 5 average rating, 116 reviewsCharming Granny Flat near SDSU & Transit Center
Guesthouse in El Cajon
4.99 out of 5 average rating, 156 reviewsModern mountain guest house. Incredible views
Guesthouse in San Diego
4.95 out of 5 average rating, 122 reviews1BR Casita in the Heart of Kensington!
Guesthouse in San Diego
4.9 out of 5 average rating, 200 reviewsSTUNNING Casita with a View!!
Guesthouse in El Cajon
4.96 out of 5 average rating, 134 reviewsMt Helix Studio Loft with Mountain Views
Guesthouse in San Diego
4.83 out of 5 average rating, 214 reviewsCozy Cottage
Quick stats about guesthouse rentals in La Mesa
Total rentals
60 properties
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Total number of reviews
3.9K reviews
Nightly prices starting at
$50 before taxes and fees
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