Skip to content

Vacation rentals in Upstate South Carolina

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Upstate South Carolina

Guests agree: these stays are highly rated for location, cleanliness, and more.

Home in Lake Toxaway
Treehouse with a Hot Tub, Hiking Trails & View
Perfect Mountain get away. A place to unplug, unwind & recharge at our fully stocked little cabin in the woods. Enjoy swinging on the porch while watching the sunset over the mountains or roast marshmallows at the outdoor fire pit. The home is an open floor plan, unique crafted cabin, circle stairs, bedroom in loft. Sit in the Hot Tub under the Stars, enjoy the private hiking trails - Also, did we mention there is a sauna!? 25 minutes to Cashiers 25 minutes to Brevard 1 hour from Asheville
$217 per night
Condo in Greenville
Centrally Located One Bedroom Loft Condo Downtown
Fantastic 1 bedroom loft condo centrally located in downtown Greenville. Easy access from a public garage directly into the building for 7.00 per night. Walk directly from the unit to everything downtown has to offer. The unit consists of a living room, kitchen, full bath, and laundry on the main level. The bedroom is located in an open loft on the second level. See all photos! Check out all of our Greenville listings and our Ft. Lauderdale location as well :)
$128 per night
Guesthouse in Greenville
The Carriage House (pet friendly)
Our cozy apartment is a 1 BR/1 BA apartment in a converted two car detached garage, on in a neighborhood that is walkable & bikable. Pet fee schedule in the description. No Cats! It is convenient to restaurants, shopping. 6 minutes to Haywood Mall, 8 minutes to downtown Greenville & 3 minutes to Woodruff road. 1.5 miles from Greenville Convention Center & Greenville downtown airport.
$89 per night

Other great vacation rentals in Upstate South Carolina

Cabin in Gatlinburg
Hard To Believe Views GSMNP/Near DwTn Gatlinburg
$127 per night
Shipping container in Walhalla
The Southern Cross at Hi Saw Gap
$121 per night
Home in Easley
“Lake House Paradise” Waterfront Oasis
$129 per night
Cabin in Sevierville
Majestic mountain view! Secluded Cabin w/ Hot Tub
$175 per night
Cabin in Sevierville
❤️ Cute Studio Cabin! Views! Private. Hot Tub. Relax!
$168 per night
Apartment in Greenville
Downtown Executive Flat
$93 per night
Bungalow in Slater-Marietta
Bungalow on the Creek
$169 per night
Apartment in Greenvillle
The View located downtown Greenville on North Main
$106 per night
Cabin in Hendersonville
Dupont State Forest Getaway Western NC
$218 per night
Home in Chimney Rock
Private romantic cabin with incredible mountain vi
$210 per night
Cabin in Gatlinburg
The Seclusion ❤️ Romantic & Private Cabin w/ STUNNING views!
$236 per night
Loft in Greenville
Romantic NYC inspired loft 5 min from downtown
$153 per night

Destinations to explore