Vacation rentals in Upstate South Carolina
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Upstate South Carolina
Guests agree: these stays are highly rated for location, cleanliness, and more.
0 of 0 items showing
1 of 3 pages
1 of 3 pages
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina vacation rentals
Other great vacation rentals in Upstate South Carolina
Superhost
Cabin in Pickens County
4.86 out of 5 average rating, 128 reviewsCozy "Sassafras Cabin" in beautiful wilderness
Guest favorite
Tiny home in Greer
4.93 out of 5 average rating, 136 reviewsShalom Tiny with Lake View - Greer, SC
Guest favorite
Home in Lyman
5.0 out of 5 average rating, 157 reviewsCozy Lakefront 2 bedroom with pool table
Guest favorite
Treehouse in Hendersonville
4.94 out of 5 average rating, 415 reviewsBeacon Treehouse
Guest favorite
Guesthouse in Greenwood
4.95 out of 5 average rating, 182 reviewsPrivate Lakefront Cabin on Lake Greenwood
Guest favorite
Cabin in Cleveland
4.99 out of 5 average rating, 156 reviewsThe Hagood House | near Pretty Place & Table Rock
Guest favorite
Treehouse in Waterloo
5.0 out of 5 average rating, 48 reviewsNew!Treehouse/lake front/hot tub
Guest favorite
Yurt in Piedmont
4.99 out of 5 average rating, 77 reviewsRomantic Farm Getaway
Destinations to explore
- Charlotte Vacation rentals
- Gatlinburg Vacation rentals
- Asheville Vacation rentals
- Pigeon Forge Vacation rentals
- Greenville Vacation rentals
- Columbia Vacation rentals
- Athens Vacation rentals
- Helen Vacation rentals
- Atlanta Vacation rentals
- Nashville Vacation rentals
- Charleston Vacation rentals
- Myrtle Beach Vacation rentals
- Rentals with beach access Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Kid-friendly rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Monthly Rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Ski-in/ski-out rentals Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Rentals with a washer and dryer Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Resort rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Condo rentals Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Wheelchair accessible rentals Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Vacation home rentals Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- House rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom