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House vacation rentals in Mesilla
Find and book unique houses on Airbnb
Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesilla house rentals
House rentals with a pool
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Home in Las Cruces
4.92 out of 5 average rating, 273 reviewsCasita at the Mediterranean Palms Estate
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Home in Las Cruces
4.88 out of 5 average rating, 132 reviewsDesert Pool Oasis-Central Location-Family Friendly
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Home in Las Cruces
4.94 out of 5 average rating, 193 reviewsPet Friendly Luxury Oasis With Pool and Hot-tub!EV
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Home in Las Cruces
4.9 out of 5 average rating, 108 reviewsAlamo on Ocotillo
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Home in Las Cruces
4.95 out of 5 average rating, 110 reviewsSecluded Red Hawk Golf & POOL Hideout
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Home in Las Cruces
4.98 out of 5 average rating, 41 reviewsCasita Nuez
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Home in Las Cruces
5 out of 5 average rating, 17 reviewsVilla Balam
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Home in Las Cruces
5 out of 5 average rating, 71 reviewsLUXURy, Heated POOl, Sunset Views, Early Check-in
Weekly house rentals
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Home in Las Cruces
4.97 out of 5 average rating, 102 reviewsDesert Retreat Near Red Hawk Golf Course
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Home in Las Cruces
4.97 out of 5 average rating, 30 reviewsJosefina's Queen Suite in Mesilla Plaza
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Home in Las Cruces
4.91 out of 5 average rating, 67 reviewsElegant 2-bedroom 2-bath Old Mesilla adobe home
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Home in Mesilla Park
5 out of 5 average rating, 14 reviewsCasa Capri, Welcome to Mesilla!
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Home in Las Cruces
5 out of 5 average rating, 67 reviewsModern Farmhouse Near Bike Path
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Home in Las Cruces
5 out of 5 average rating, 13 reviewsPecan Palace w/ EV charger & HOT TUB (Near NMSU)
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Home in Las Cruces
4.95 out of 5 average rating, 79 reviewsLuxury Southwest Retreat
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Home in Mesilla Park
4.97 out of 5 average rating, 36 reviewsConway Cottage 5-1
Private house rentals
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Home in Las Cruces
4.96 out of 5 average rating, 54 reviewsCasa Tortugas! Near NMSU and Old Mesilla!
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Home in Las Cruces
5 out of 5 average rating, 17 reviewsCozy Las Cruces Home
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Home in Las Cruces
4.91 out of 5 average rating, 58 reviewsShadow Mountain near NMSU
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Home in Las Cruces
5 out of 5 average rating, 26 reviewsBright, airy 2BR close to nature
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Home in Las Cruces
5 out of 5 average rating, 7 reviewsLa Casita de Frida
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Home in Las Cruces
4.97 out of 5 average rating, 59 reviewsSouthwestern Comfort Stay 2
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Home in Las Cruces
4.9 out of 5 average rating, 31 reviewsYour modern home away from home 3BR 2 BTH
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Home in Las Cruces
5 out of 5 average rating, 21 reviewsModern Comfort - New Townhome
Quick stats about house rentals in Mesilla
Total rentals
30 properties
Nightly prices starting at
$60 before taxes and fees
Total number of reviews
2K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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