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Vacation rentals in Lake Saint Louis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lake Saint Louis

Guests agree: these stays are highly rated for location, cleanliness, and more.

Private & Modern Detached Guesthouse with views!
Entire guesthouse · 6 guests · 3 beds · 1.5 baths
Private & Modern Detached Guesthouse with views!Forget your worries in this spacious and serene space. Surrounded by 5.5 acres of wooded land to be enjoyed by two levels of wrap around decking for those cozy nights outdoors. Step inside for modern comfort and relaxing views. Just minutes from “The Meadows” shopping, restaurants and bars of Lake Saint Louis. With down town St. Louis only 35 minutes away and St Charles Main Street just 25 minutes away. There are endless possibilities to keep you entertained!
Treehouse Spa Suite
SUPERHOST
Treehouse · 2 guests · 1 bed · 1 bath
Treehouse Spa SuiteDesigned and built by Dave. Inspired by God. Enjoyed by you! There are two rental units in the treehouse: The spa suite and the penthouse. They each have a separate entrance and have private spaces. Recharge your battery! Regroup Relax Refresh Construction all around me but I still have my trees! The trees next door to me are gone!! Come see it! Come experience it! Unique ! Inspired ! May the Lord Bless you and Protect you and give you Peace
Updated Farmhouse 
2 bd 2 acres
SUPERHOST
Farm stay · 5 guests · 3 beds · 1 bath
Updated Farmhouse 2 bd 2 acresUpdated Farm House on 2 acres, this house has 2 bedrooms, a kitchen and living room, this house is a duplex, with 2 separate units, the upstairs is for Airbnb guest, the lower unit has a tenant, each unit has its own space and entrance. 25 minutes from the St. Louis Airport, close to the Missouri Wineries, and only 10 minutes to the Katie Trail along the Missouri River. only 15-25 minutes to the Missouri Wineries.

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Other great vacation rentals in Lake Saint Louis

SUPERHOST
  1. Entire loft
  2. Wentzville
Lovely one bedroom studio apartment.
$125 per night
SUPERHOST
  1. Entire condominium (condo)
  2. Dardenne Prairie
Dream Away Lodge - Amazing Location
$52 per night
  1. Private room
  2. O'Fallon
Beautiful suburb home with private room
$55 per night
SUPERHOST
  1. Private room
  2. O'Fallon
Uncle Eddie's Camper
$42 per night
  1. Entire residential home
  2. O'Fallon
Luxurious 4 bedroom contemporary home.
$250 per night
SUPERHOST
  1. Entire residential home
  2. Wentzville
Gorgeous ranch style home in heart of Wentzville
$146 per night
SUPERHOST
  1. Entire residential home
  2. O'Fallon
Golf Heaven and Nature Lovers
$350 per night
SUPERHOST
  1. Entire serviced apartment
  2. Wentzville
🍇Beautuful Main LVL w/No Stairs! Central Location
$317 per night
  1. Entire residential home
  2. O'Fallon
Brand new basement in a beautiful lake view house
$140 per night
  1. Private room
  2. Lake Saint Louis
A bedroom in beautiful house with a lake view (1)
$75 per night
  1. Entire residential home
  2. Lake Saint Louis
Lake Saint Louis Family Friendly Lakefront Retreat
$224 per night
  1. Private room
  2. O'Fallon
Agatha House, quiet in cul de sac, no cleaning fee
$49 per night