Vacation rentals in St. Charles County
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Top-rated vacation rentals in St. Charles County
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
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Popular amenities for St. Charles County vacation rentals
Other great vacation rentals in St. Charles County
Guest favorite
Home in Godfrey
4.89 out of 5 average rating, 209 reviewsPrivate, Bluff-Top Cottage Above Mississippi River
Jan 24 – 31
$91 per night
Guest favorite
Guest suite in Dardenne Prairie
4.89 out of 5 average rating, 196 reviewsTreehouse Spa Suite
Jun 29 – Jul 6
$68 per night
Guest favorite
Home in Saint Charles
4.99 out of 5 average rating, 157 reviewsCharming Bungalow in Historic St. Charles, MO
Mar 4 – 11
$262 per night
Guest favorite
Loft in Saint Charles
4.81 out of 5 average rating, 43 reviewsCity Loft in Saint Charles
Jul 24 – 31
$97 per night
Guest favorite
Home in Saint Charles
4.88 out of 5 average rating, 57 reviewsThe robin nest a cozy cottage on historic main str
Sep 12 – 19
$102 per night
Guest favorite
Home in Saint Charles
4.9 out of 5 average rating, 10 reviewsFenced St. Charles Charmer
Dec 15 – 22
$108 per night
Guest favorite
Guesthouse in St. Peters
4.93 out of 5 average rating, 30 reviewsMaple Tree Enchanted Guest House 1 bedroom 2 beds
Jan 17 – 24
$71 per night
Guest favorite
Home in Saint Charles
5.0 out of 5 average rating, 23 reviewsLittle House By Main St -5 4K TV's- 1-75 Inch -1GB
Oct 18 – 25
$155 per night
Destinations to explore
- Condo rentals St. Charles County
- Rentals with a patio St. Charles County
- Rentals with a washer and dryer St. Charles County
- Rentals with lake access St. Charles County
- Rentals with outdoor seating St. Charles County
- Rentals with a fireplace St. Charles County
- Private suite rentals St. Charles County
- Rentals with pools St. Charles County
- Rentals with a hot tub St. Charles County
- Rentals with breakfast St. Charles County
- Loft rentals St. Charles County
- Fitness-friendly rentals St. Charles County
- Pet-friendly rentals St. Charles County
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- Rentals with an accessible height toilet St. Charles County
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- Apartment rentals St. Charles County
- Rentals with an EV charger St. Charles County
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- House rentals St. Charles County
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- Monthly Rentals St. Charles County
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