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Vacation rentals in Florence

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Florence

Guests agree: these stays are highly rated for location, cleanliness, and more.

Apartment in Florence
Kuker Carriage House-Sleeps 3-Downtown/Near I95&20
Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20
$101 per night
Guest suite in Florence
Private Apartment 5 Min Away From I-95 & I-20
Please come and enjoy our Guest Apartment in Florence, SC! A great stop for travelers to rest during their trips. Guests will have a private entrance to the apartment that is attached but separate from the main house, where me and my family live. Guest privacy will always be respected. One bedroom has a queen size bed, a second bedroom has a daybed. The bathroom has a tub and shower. The kitchen has a stove/oven. The apartment is cleaned and sanitized after each guest leaves. Thank you!
$75 per night
Guesthouse in Florence
The Poolside Cottage: Close to Interstates
New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
$102 per night

Stay near Florence's top sights

Walmart Neighborhood Market4 locals recommend
Florence Center3 locals recommend
Red Bone Alley Restaurant15 locals recommend
Percy & Willies3 locals recommend
Tubb's Shrimp and Fish Co.9 locals recommend
The Drive In3 locals recommend

Other great vacation rentals in Florence

Cottage in Timmonsville
*Cottage Near Florence and I-95*
$99 per night
Home in Effingham
Clean and Comfortable 3B/2B Home w/ 2-Car Garage
$82 per night
Apartment in Lake City
Home away from Home #5 - Stay Smart-Save
$54 per night
Cottage in Florence
DOWNTOWN Pine Cottage
$68 per night
Home in Florence
Pineapple House Historic Southern Charm Downtown
$80 per night
Home in Florence
Bright, Airy, and Convenient Home on King
$90 per night
Bungalow in Florence
Quaint Bungalow in Historic Downtown Florence
$123 per night
Condo in Florence
Modern 1 bedroom condo near downtown Florence
$80 per night
Apartment in Florence
Modern 3B/2Ba Condo- Sleeps 6, near Civic Center
$159 per night
Home in Florence
Cozy home in Florence, SC
$113 per night
Townhouse in Florence
Crystal Green House
$103 per night
Home in Florence
Calm with scenic views near 5 points Starbucks
$70 per night

Destinations to explore