House vacation rentals in Des Moines
Find and book unique houses on Airbnb
Top-rated house rentals in Des Moines
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Des Moines house rentals
House rentals with a pool
Home in Urbandale
LONG TERM 7 BR 4 Bath w/14 Beds
Home in Ankeny
4.86 out of 5 average rating, 42 reviewsComfortable and Spacious Five Bedroom Home
Home in West Des Moines
4.69 out of 5 average rating, 13 reviewsWest Des Moines modern mansion!
Home in Urbandale
4.96 out of 5 average rating, 55 reviewsThe Estate
Home in Urbandale
3.5 out of 5 average rating, 4 reviewsBrick 3 BR Ranch weekly rate at $99 per night
Home in West Des Moines
New place to stayGraceland Acreage w/ Party Barn!
Home in Des Moines
4.79 out of 5 average rating, 62 reviewsUrban Oasis
Home in Historic East Village
4.82 out of 5 average rating, 72 reviewsThe Capitol House-East Village/Downtown, King Bed
Weekly house rentals
Home in Clive
4.88 out of 5 average rating, 76 reviewsFamily-Oriented 5 BR Home with Hot Tub & Game Room
Home in Des Moines
4.71 out of 5 average rating, 63 reviewsCute 2-bedroom / 1 bath house completely remodeled
Home in Des Moines
4.85 out of 5 average rating, 267 reviewsCozy Spa Home Close to Downtown
Home in Urbandale
4.81 out of 5 average rating, 134 reviewsCozy home with 4 bedroom in Urbandale
Home in Des Moines
4.92 out of 5 average rating, 172 reviewsCheerful 2 bedroom, 3 bed home near Adventureland
Home in West Des Moines
4.79 out of 5 average rating, 107 reviewsBudget friendly upstairs apartment in duplex!
Home in Waukee
4.99 out of 5 average rating, 94 reviewsWaukee Guest House - Close to everything in DSM
Home in Ankeny
4.98 out of 5 average rating, 61 reviewsSaylorvilla ~ Tesla Charger
Private house rentals
Home in Des Moines
4.82 out of 5 average rating, 61 reviewsJoshua's Northland Bungalow
Home in Des Moines
4.89 out of 5 average rating, 401 reviewsGarden Retreat Near Downtown, Botanical Immersion
Home in Norwalk
4.91 out of 5 average rating, 43 reviewsVictoria's House at Rose Farm
Home in Des Moines
4.93 out of 5 average rating, 230 reviewsFully Fenced Story Book Cottage, close to downtown
Home in Perry
4.99 out of 5 average rating, 70 reviewsHistoric Home in the Heart of Perry
Home in Des Moines
4.89 out of 5 average rating, 47 reviewsThree Pines by Drake King Bed
Home in Madrid
4.94 out of 5 average rating, 34 reviewsTrailside Inn - Whole House
Home in Perry
5 out of 5 average rating, 48 reviewsExcellent Home in Perry with 4 Bedrooms/4 Beds.
Quick stats about house rentals in Des Moines
Total rentals
400 properties
Total number of reviews
22K reviews
Family-friendly rentals
280 properties are a good fit for families
Pet-friendly rentals
160 properties allow pets
Rentals with dedicated workspaces
250 properties have a dedicated workspace
Wifi availability
390 properties include access to wifi
Destinations to explore
- Ames Vacation rentals
- Pella Vacation rentals
- West Des Moines Vacation rentals
- Waterloo Vacation rentals
- Ankeny Vacation rentals
- Cedar Falls Vacation rentals
- Lake View Vacation rentals
- Fairfield Vacation rentals
- Lake Red Rock Vacation rentals
- Waverly Vacation rentals
- Boone Vacation rentals
- Lake Panorama Vacation rentals
- Earth house rentals United States
- Lighthouse rentals United States
- Guesthouse rentals United States
- House rentals United States
- Townhouse rentals United States
- Rentals with breakfast Des Moines
- Rentals with an EV charger Des Moines
- Pet-friendly rentals Des Moines
- Rentals with a fireplace Des Moines
- Rentals with a patio Des Moines
- Rentals with outdoor seating Des Moines
- Rentals with a hot tub Des Moines
- Apartment rentals Des Moines
- Rentals with a fire pit Des Moines
- Rentals with a washer and dryer Des Moines
- Monthly Rentals Des Moines
- Fitness-friendly rentals Des Moines
- Kid-friendly rentals Des Moines
- Townhouse rentals Iowa
- Lakehouse rentals Iowa
- House rentals Iowa
- Guesthouse rentals Iowa
- Tiny house rentals Iowa
- Townhouse rentals Iowa
- Lakehouse rentals Iowa
- House rentals Iowa
- Guesthouse rentals Iowa
- Tiny house rentals Iowa
- House rentals Ames
- Townhouse rentals Polk County
- House rentals Polk County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom