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House vacation rentals in Cape Girardeau
Find and book unique houses on Airbnb
Top-rated house rentals in Cape Girardeau
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Cape Girardeau house rentals
House rentals with a pool
![](https://a0.muscache.com/im/pictures/miso/Hosting-30827657/original/70206372-b7a1-4bcf-b190-574537762196.jpeg?im_w=720)
Home in Carbondale
4.75 out of 5 average rating, 126 reviewsBrick Estate with pool in Quiet Neighborhood
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Home in Cobden
4.93 out of 5 average rating, 40 reviewsSkyline Getaways
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Home in Murphysboro
5 out of 5 average rating, 78 reviewsEmbers of Murphysboro
![](https://a0.muscache.com/im/pictures/miso/Hosting-47593442/original/bd2c9eb6-7b4a-42f5-aed1-8616c175d83a.jpeg?im_w=720)
Home in Park Hills
4.98 out of 5 average rating, 58 reviewsBluebird Meadows w/ Hot Tub and Pool **Special***
![](https://a0.muscache.com/im/pictures/miso/Hosting-914361685369426109/original/fbb35204-d6cf-4188-9144-20febd995e1c.jpeg?im_w=720)
Home in Farmington
4.82 out of 5 average rating, 17 reviews3-bedroom, 2.5-bath 'Barn Loft'
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Home in Du Quoin
4.94 out of 5 average rating, 33 reviewsPeninsula Paradise - North
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Home in Creal Springs
4.92 out of 5 average rating, 12 reviewsLake Views & Access + Private Pool, Pets OK
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Home in Du Quoin
4.89 out of 5 average rating, 145 reviewsMarsha's Guesthouse Rental
Weekly house rentals
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Home in Cape Girardeau
4.79 out of 5 average rating, 34 reviews3 Bed Bungalow w/ Deck and Fenced-In Back Yard
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Home in Cape Girardeau
4.83 out of 5 average rating, 69 reviews3 Bed Adorable Home: Next to Hospital + SEMO
![](https://a0.muscache.com/im/pictures/cc005b85-8279-4291-adf7-b276785da88c.jpg?im_w=720)
Home in Cape Girardeau
4.91 out of 5 average rating, 46 reviewsCozy Cottage
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Home in Cape Girardeau
5 out of 5 average rating, 12 reviewsCapeG Historic Home [downtown]
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Home in Cape Girardeau
4.9 out of 5 average rating, 10 reviewsAccessible, comfortable family home for 12+
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Home in Cape Girardeau
4.95 out of 5 average rating, 22 reviewsCharming 2-Story- C.1847 - River Views - Fast Wifi
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Home in Bloomfield
4.94 out of 5 average rating, 47 reviewsBloomfield Bungalow
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Home in Cobden
4.98 out of 5 average rating, 40 reviewsWine trail cozy cabin! Hot Tub!
Private house rentals
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Home in Alto Pass
4.97 out of 5 average rating, 33 reviewsAlto Cabin-AUG DEAL. 20% off stay
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Home in Anna
5 out of 5 average rating, 10 reviews150 year old charmer!
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Home in Sikeston
5 out of 5 average rating, 8 reviewsEmma’s Cottage
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Home in Farmington
5 out of 5 average rating, 52 reviewsColumbia Street Carriage House
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Home in Piedmont
4.88 out of 5 average rating, 8 reviewsCozy Cabin on a Beautiful River
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Home in Sikeston
4.93 out of 5 average rating, 73 reviewsNeuberry Cottage
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Home in Cape Girardeau
4.87 out of 5 average rating, 15 reviewsSEMO Redhawks Campus Home with Hot Tub
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Home in Cadet
4.99 out of 5 average rating, 95 reviews2BR House with Hot Tub near Washington State Park!
Quick stats about house rentals in Cape Girardeau
Total rentals
70 properties
Nightly prices starting at
$20 before taxes and fees
Total number of reviews
3.1K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
50 properties have a dedicated workspace
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