House vacation rentals in Port St. Lucie
Find and book unique houses on Airbnb
Top-rated house rentals in Port St. Lucie
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Port St. Lucie house rentals
House rentals with a pool
Home in Jensen Beach
4.91 out of 5 average rating, 155 reviewsNettles Island rental
Nov 1 – 8
Home in Port St. Lucie
4.91 out of 5 average rating, 109 reviewsFlorida Oasis " BEAUTIFUL HEATED POOL HOME "
Nov 14 – 21
Home in Jensen Beach
4.82 out of 5 average rating, 142 reviewsIsland Breeze
Jun 14 – 21
Home in Jensen Beach
4.97 out of 5 average rating, 119 reviewsMini-Golf*Heated Saltwater Pool*New*Lake Front!
Dec 30 – Jan 6
Home in Port St. Lucie
5.0 out of 5 average rating, 59 reviewsCoastal Gem: Pool, Hot Tub, King Bed, & Game Room
Sep 22 – 29
Home in Port St. Lucie
4.94 out of 5 average rating, 17 reviewsVacation Home With Private Pool In Port St. Lucie
Jun 18 – 25
Home in Port St. Lucie
4.95 out of 5 average rating, 20 reviewsFamily Friendly Pool home near the beach!
Oct 19 – 26
Home in Port St. Lucie
4.89 out of 5 average rating, 80 reviews3BR Golfers Paradise in Sunny South Florida
Sep 18 – 25
Weekly house rentals
Home in Jensen Beach
4.94 out of 5 average rating, 31 reviewsJensen Beach Bungalow 2!
May 31 – Jun 7
Home in Port St. Lucie
4.88 out of 5 average rating, 40 reviewsBeautiful 3 Bed, 2 Bath Golf Course Home
Aug 10 – 17
Home in Port St. Lucie
4.88 out of 5 average rating, 43 reviewsEntire Home:Come enjoy! Two Bedroom two bath home!
Aug 25 – Sep 1
Home in Port St. Lucie
4.9 out of 5 average rating, 29 reviewsBrand New! Disney & Beaches: PSL Gem!
Sep 2 – 9
Home in Port St. Lucie
5.0 out of 5 average rating, 20 reviewsThe boathouse
Jun 13 – 20
Home in Port St. Lucie
4.94 out of 5 average rating, 33 reviewsCameo House
Jan 1 – 8
Home in Fort Pierce
4.97 out of 5 average rating, 69 reviewsFamily Friendly Tropical Escape @The Coconut House
Aug 21 – 28
Home in Port St. Lucie
5.0 out of 5 average rating, 14 reviews“The Mango House” Family Paradise - Beach/METS/PGA
Oct 4 – 11
Private house rentals
Home in Jensen Beach
5.0 out of 5 average rating, 96 reviewsTropical Way Getaway
Oct 27 – Nov 3
Home in Port St. Lucie
4.85 out of 5 average rating, 27 reviews12 mins from beach! Cozy 3 bdr w private backyard.
Sep 23 – 30
Home in Port St. Lucie
4.97 out of 5 average rating, 34 reviewsThe Canary House
Oct 18 – 25
Home in Port St. Lucie
4.99 out of 5 average rating, 72 reviewsOcean Cove Getaway
Aug 25 – Sep 1
Home in Port St. Lucie
4.96 out of 5 average rating, 28 reviewsWaterfront Oasis | Luxury Amenities-& Kayaks
Nov 12 – 19
Home in Stuart
5.0 out of 5 average rating, 15 reviewsSunny Spacious Home in Stuart!
Jun 26 – Jul 3
Home in Port St. Lucie
5.0 out of 5 average rating, 26 reviewsHeated pool. Private back yard.
Apr 14 – 21
Home in Port St. Lucie
5.0 out of 5 average rating, 31 reviewsUpscale by Beach Golf * Private Pool * Luxe Oasis
Jan 10 – 17
Quick stats about house rentals in Port St. Lucie
Total rentals
780 properties
Rentals with dedicated workspaces
440 properties have a dedicated workspace
Rentals with a pool
350 properties have a pool
Pet-friendly rentals
300 properties allow pets
Family-friendly rentals
540 properties are a good fit for families
Total number of reviews
15K reviews
Destinations to explore
- West Palm Beach Vacation rentals
- Boca Raton Vacation rentals
- Fort Lauderdale Vacation rentals
- Kissimmee Vacation rentals
- Miami Beach Vacation rentals
- Miami Vacation rentals
- Orlando Vacation rentals
- Naples Vacation rentals
- Sarasota Vacation rentals
- Tampa Vacation rentals
- Anna Maria Island Vacation rentals
- Key West Vacation rentals
- Earth house rentals United States
- House rentals United States
- Guesthouse rentals United States
- Townhouse rentals United States
- Lighthouse rentals United States
- Tiny house rentals Florida
- Lakehouse rentals Florida
- Townhouse rentals Florida
- Guesthouse rentals Florida
- House rentals Florida
- Beach house rentals Florida
- Tiny house rentals Florida
- Lakehouse rentals Florida
- Townhouse rentals Florida
- Guesthouse rentals Florida
- House rentals Florida
- Beach house rentals Florida
- House rentals Fort Lauderdale
- Beach house rentals Fort Lauderdale
- Townhouse rentals Fort Lauderdale
- Guesthouse rentals Fort Lauderdale
- House rentals Kissimmee
- Guesthouse rentals Kissimmee
- Townhouse rentals Kissimmee
- Tiny house rentals Kissimmee
- Rentals with lake access Port St. Lucie
- Kid-friendly rentals Port St. Lucie
- Rentals with a washer and dryer Port St. Lucie
- Rentals with a hot tub Port St. Lucie
- Rentals with a patio Port St. Lucie
- Pet-friendly rentals Port St. Lucie
- Rentals with a fireplace Port St. Lucie
- Rentals with beach access Port St. Lucie
- Apartment rentals Port St. Lucie
- Family-friendly rentals Port St. Lucie
- Condo rentals Port St. Lucie
- Monthly Rentals Port St. Lucie
- Waterfront rentals Port St. Lucie
- Smoking-friendly rentals Port St. Lucie
- Rentals with pools Port St. Lucie
- Rentals with outdoor seating Port St. Lucie
- Rentals with a fire pit Port St. Lucie
- Fitness-friendly rentals Port St. Lucie
- House rentals St. Lucie County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom