Guesthouse vacation rentals in Pima County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Pima County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Tucson

4.9 out of 5 average rating, 811 reviews

The Hummingbird, a very tranquil

The Hummingbird, (SELF CHECK-IN ,) is a very tranquil sanctuary in Central Tucson: Part of almost an acre walled compound with a view to the north of the Catalina Mountains. A private driveway from the road gives you access to your own gated “keyless” entry and secure parking and fenced yard. A Santa Fe style door opens to a private walled patio and entrance P.S. Reservations for longer than 3 nights fall under the “ Strict Cancellation” rule, as do Reservation between 1/25 - 2/10 (Gem Show).

Guest favorite

Guesthouse in Tucson

4.95 out of 5 average rating, 820 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite

Guesthouse in Tucson

5 out of 5 average rating, 253 reviews

Cottage

Casita Rosada is a converted artist's studio in the Tucson Mountain foothills surrounded by native desert vegetation yet only 15 minutes from downtown. A bright, spacious interior decorated in the Southwest tradition, twelve foot ceilings, comfy chairs, and a pillow-top queen bed make it your ideal home away from home. Have coffee on the porch and watch the sunrise, observe wildlife, gaze at the mountains, and view the city lights each night. Hiking trails and bike paths are both within a mile.

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 396 reviews

Studio in the Saguaro Forest

New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 310 reviews

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 145 reviews

Central cozy casita with private yard!

Renovated 1950's territorial revival features a taste of the desert with modern amenities! The casita features a comfortable pillow top queen bed and an additional twin bed, full sized closet, beautiful bathroom that was featured on Styled by Emily Henderson DIY Bathroom renovations, kitchenette with pantry, mini fridge, microwave, countertop oven and hot plate, and a private yard with outdoor dining and space for relaxing. Plentiful parking, wifi and AC and heat will make your stay a breeze!

Guest favorite

Guesthouse in Tucson

4.97 out of 5 average rating, 735 reviews

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 178 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Guest favorite

Guesthouse in Tucson

4.98 out of 5 average rating, 366 reviews

No Cleaning Fees!

Guest Quotes: "Coziness of an Airbnb & the amenities of a five-star hotel. Special touches are so welcoming! Sunrise and sunsets from the deck are spectacular! Perfect mix of City amentities & desert peace. Best Airbnb experience ever. Love the wildlife. Like your own personal botanical garden. Host was attentive but not intrusive. We felt right at home. Charming, Magical, Spacious, Peaceful, Comfortable, Beautiful, Amazing. Extremely Clean. A sanctuary in uncertain times."

Guest favorite

Guesthouse in Ajo

4.99 out of 5 average rating, 183 reviews

Cozy hideaway cottage in historic Ajo

Stay in a cozy, very private, window filled 500 sq. ft. hideaway cottage that is located on the property of a historic Ajo home. Located just 4 blocks from the gorgeous Spanish Revival town plaza, you can walk to Ajo's Visitors Center, art galleries, restaurants, library, and coffee shop or you can drive a mile to the Ajo Scenic Loop to savor and hike a portion of the pristine Sonoran Desert that rivals Organ Pipe Cactus National Monument. Let me welcome you to Ajo!

Guest favorite

Guesthouse in Tucson

4.97 out of 5 average rating, 265 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in the Sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge in the sun or shade on the deck or under louvered patios. Close to the UA and downtown. Book now and escape the ordinary!

Guest favorite

Guesthouse in Rio Rico

4.87 out of 5 average rating, 332 reviews

Cozy Rio Rico guesthouse with a view

This spacious guesthouse is in an ideal rural setting. Located near the Mexican border, the art community at Tubac, and the old Spanish mission of Tumacacori, there is lots to see and do. (Not to mention many good golf courses.) I am looking forward to your visit! To make your stay both pleasant and sanitary I steam clean floors, sani-wash all linens and towels, and wipe counters, sinks and toilet with sanitizer spray. Rest easy here!