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Weekend vacation rentals in Mississippi

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Mississippi

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Treehouse in Tishomingo
Fern Hollow Treehouse Escape, cozy romantic!
You'll love this unique and romantic escape.❤️❤️❤️ we are pet friendly Treehouse is very rustic. Sawmill or reclaimed wood with natural tree handrails This is a glamping experience kinda place. If you love outdoors you will love if here in this natural setting. The kitchen/dinning is in the first building up the stairs across a catwalk is the bed/bathroom. There is a pond in the field if you like to fish. Need extra space? There is plenty room to put up a tent.. come enjoy Fern Hollow.
$175 per night
Cabin in Gloster
Thunder Ridge —Entire House pet-friendly near NOLA
Thunder Ridge at the Forest Retreat is an adults-only pet-friendly getaway. Children may come only during specific holidays. Your house will be unlocked. Check-in is a 3 p.m. Here you are surrounded by the Homochitto National Forest. Take a picnic to the sand-bars along the pristine spring-fed creek. Hike or mountain bike on the remote forest roads. Plenty of porch sitting awaits you. Please note that the address listed on Airbnb is not our location. I will email you directions.
$144 per night
Loft in Kiln
Enchanting 'Whitney Cabin' w/ Beach & Creek!
Framed by lush green foliage and sparkling outdoor lights, this ultra-cozy 1-bath studio looks straight out of a fairytale. Aside from the chic, newly renovated interior, other home highlights include a screened porch, a spacious deck, a creekside trail, and no shortage of scenic views. Spend your days exploring to your heart's content, and falling asleep each night to the soothing soundtrack of the on-site creek. Craving more beach time? The Biloxi coast is less than 20 miles away.
$106 per night

Vacation rentals in Mississippi

Home in Gulfport
Cozy cottage by the Sea -near downtown with patio!
$97 per night
Cottage in Poplarville
Three Creeks Cottage (Popatop)
$120 per night
Home in Corinth
The Farmhouse, Corinth MS
$145 per night
Rental unit in Biloxi
$100 per night
Cottage in Bay St. Louis
Bay-Cay Getaway! Beaching-Casino-Grilling-Swimming
$85 per night
Guest suite in Ocean Springs
Hillside Hideaway Downtown Studio B&B Pool Gardens
$100 per night
Cabin in Meadville
Getaway Homochitto - New Orleans
$117 per night
Treehouse in Magnolia
Mar I-Wilya
$110 per night
Cabin in Summit
Firefly Lane Cabin 3 In Southwest Mississippi
$84 per night
Cabin in Poplarville
The Creekside Cabin Retreat #1
$152 per night
Guest suite in Ocean Springs
Pineapple Palms Downtown Loft B&B Pool Gardens
$90 per night
Rental unit in Jackson
The Artistry) Apt in Jackson (Midtown)
$71 per night

Family friendly vacation rentals in Mississippi

Cabin in Forest
Homewood Hideaway
$94 per night
Condo in Biloxi
Beach Getaway
$79 per night
Cabin in McComb
Love Creek Cabin at Fortenberry Farm
$96 per night
Bungalow in Long Beach
Shell House Estate Bungalow
$150 per night
Guesthouse in Laurel
The Laurel Cottage - stay with Mallorie!
$222 per night
Townhouse in Ocean Springs
Marina Townhouse
$55 per night
Home in Natchez
'Lazy Daisy' Charming two bedroom cottage!
$125 per night
Cottage in Coldwater
Wynnewood - Elizabeth Cottage
$115 per night
Hotel room in Bay Saint Louis
The Happy Place
$103 per night
Private room in Biloxi
ROOM In Gorgeous Home on The Bay + Kayak Rental
$66 per night
Condo in Biloxi
Beach Comber
$89 per night
Condo in Biloxi
Ground Floor Beach & Casino Getaway!
$80 per night

Your guide to Mississippi

Welcome to Mississippi

The Mississippi River fertilizes huge swaths of the United States with its water, and the state that takes its name does the same with much of its culture and history. Visiting Mississippi steeps you in the roots of American music, winds you past historic battlefields, and deposits you on the Gulf Coast to savor the seafood. You can visit the birthplaces of musical royalty, but also listen to the next generation of stars at juke joints in the Delta. Similarly, the Mississippi Civil Rights Museum continues the story told by the nearby Vicksburg National Military Park, showing how the fight for freedom has continued since the Civil War. In the far south of the state, another body of water shapes Mississippi, as the 44 miles of Gulf Coast shoreline boast beaches, phenomenal seafood, and expanses of water ideal for kayaking, paddleboarding, and fishing.

When is the best time to stay in a vacation rental in Mississippi?

Long, hot summers blanket the state in humidity for much of the year, ending as hurricane season peaks in September, making the best times to visit late fall and early spring, when temperatures are more moderate. Events are mainly scheduled for those shoulder seasons to capitalize on that milder weather, and often they center on the state’s culinary prowess, like the Biloxi Seafood Fest, Gulfport’s Country Cajun Crawfish Festival, and Greenwood’s Que on the Yazoo.

What are the top things to do in Mississippi?

Natchez Trace

The Natchez Trace Parkway and the parallel Natchez Trace Trail cover 444 miles across the South, with more than 300 in Mississippi, following a travel path originated by Native Americans thousands of years ago. The Parkway’s visitor center is in Tupelo, but you can camp, hike, bike, and drive your way along the route, staying in cabins along the way, and starting or stopping at memorials, state parks, and unique natural sites.


Biloxi brings together beautiful white sand beaches, succulent Gulf Coast seafood, and a long history dating back to the 17th century. It’s a great base for exploring the state’s natural wonders and Southern hospitality. It’s also known for its championship golf courses.

The Delta

The state’s culture-rich northwest corner features a maze of backroads leading to juke joints, barbecue restaurants, and friendly small towns. Stop for ribs and pie, listen to live music in the birthplace of the blues, and visit the occasional Civil Rights memorial or haunted house along the way. The region’s wealth of fascinating spots makes travel here easy — just get on the road and see what you find.