Vacation rentals in Mayo Lake

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Top-rated vacation rentals in Mayo Lake

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite
Apartment in Rougemont
Cozy Rougemont Studio w/Walking Trails - Farm Time
Welcome! Our newly renovated Farm Time studio, with full kitchen, is perfect for a quiet get away. Nestled among a lush treeline and picturesque pond, this 1-bathroom apartment with queen bed and full sleeper sofa, is the perfect place to relax. Spend crisp mornings strolling through the green fields or enjoy a fire overlooking the pond at night. There’s also plenty to do in nearby Hillsborough (10 miles) and Durham (18 miles) - museums, parks, markets, and restaurants. RDU Airport (34 miles).
Jun 27 – Jul 4
$81 per night
4.96 out of 5 average rating, 158 reviews
Guest favorite
Place to stay in Roxboro
Original Midcentury Modern "Glass House on Hyco"
Very unique architecture on Hyco Lake! The glass walls on the main level provide excellent natural lighting! Wood exposed beams, huge glass windows, harwood floors, concrete wood burning fireplace, updated kitchen, huge screened in porch opened to the main living area all add to the beauty of this midcentury modern property. The boat dock provides lake access where the paddle boards and kayaks are available to guests! Miles from VIR raceway and convenient to the Triangle & Triad areas!
Apr 11 – 18
$399 per night
4.99 out of 5 average rating, 313 reviews
Guest favorite
Cabin in Roxboro
Water Front Lake House!
Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Direct TV, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water and dock, hammock and fire pit. Lots of fishing, single kayak, 2 person kayak, canoe and paddle boat available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC
Feb 9 – 16
$116 per night
4.87 out of 5 average rating, 147 reviews

Popular amenities for Mayo Lake vacation rentals

Other great vacation rentals in Mayo Lake

Guest favorite
Cabin in Hillsborough
Artist's Studio
Apr 27 – May 4
$125 per night
4.99 out of 5 average rating, 249 reviews
Guest favorite
Cottage in South Boston
Lady in Red
Oct 18 – 25
$158 per night
5.0 out of 5 average rating, 105 reviews
Guest favorite
Tiny home in Chapel Hill
Chic Modern Tiny House Nestled in the Trees
Apr 16 – 23
$84 per night
4.93 out of 5 average rating, 584 reviews
Guest favorite
Guesthouse in Saxapahaw
The Yurt at Frog Pond Farm
Aug 22 – 29
$104 per night
4.92 out of 5 average rating, 684 reviews
Guest favorite
Cabin in Roxboro
Moonlight Cabin - Lakefront Stay
May 6 – 13
$197 per night
5.0 out of 5 average rating, 27 reviews
Guest favorite
Home in Roxboro
Long’s Lakehouse
Apr 8 – 15
$127 per night
5.0 out of 5 average rating, 23 reviews
Guest favorite
Home in Roxboro
Private Lakefront Paradise - Paddleboards & Kayaks
Oct 15 – 22
$293 per night
4.98 out of 5 average rating, 45 reviews
Guest favorite
Home in Roxboro
Private Lakefront Mayo Hideaway: Sleeps 12 Guests
Oct 31 – Nov 7
$258 per night
5.0 out of 5 average rating, 42 reviews
Guest favorite
Home in Roxboro
Rustic Lakehouse Oasis-Hot Tub, Game Room, FirePit
Aug 13 – 20
$404 per night
4.92 out of 5 average rating, 26 reviews
Guest favorite
Home in Roxboro
Sleeps 17, American Indian owned
Jul 20 – 27
$198 per night
4.94 out of 5 average rating, 18 reviews
Guest favorite
Guesthouse in Leasburg
NEW! Hyco Lake Gem w/ game room
Mar 12 – 19
$119 per night
4.89 out of 5 average rating, 18 reviews
Superhost
Home in Roxboro
Sueños Hyco Lakeside Retreat, close to VIR!
Apr 10 – 17
$473 per night
5.0 out of 5 average rating, 5 reviews

Destinations to explore