Mark Twain Lake vacation rentals

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Top-rated vacation rentals in Mark Twain Lake

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Guest favorite

Cabin in Perry

4.89 out of 5 average rating, 44 reviews

Mark Twain Lake Cabin at Cedar Crest Place

Enjoy the Mark Twain Lake area with your own cabin, ideally located just minutes from a wide range of amenities. Whether you are planning on getting out on the lake, exploring the surrounding area, or simply looking for a quiet place to relax this cabin is an ideal fit. Includes ample sleeping to accommodate up to 8, roku-equipped TVs, 1GB wifi, a large firepit, deck with grill, and hot tub. Centrally located only minutes from restaurants, Blackjack Marina, fishing, shooting, and hiking spots.

Guest favorite

Home in Quincy

4.99 out of 5 average rating, 115 reviews

The Spruce House

The Spruce House is a beautifully restored and fully updated 1930's style bungalow with all the modern amenities! The interior of the cozy home has been remodeled to meet all of your needs while traveling to Quincy. Located near Blessing Hospital and only four blocks from Quincy University's Q-Stadium, The Spruce House offers a beautiful kitchen, two bed rooms with king and queen beds, high-speed Wi-Fi, a spacious yard, off street parking and a wonderful and safe neighborhood. Let us host you!

Guest favorite

Rental unit in Madison

4.98 out of 5 average rating, 128 reviews

Enjoy a Relaxing 2 Bed. Apt. in Quiet Small Town

The fully furnished apartment provides a quiet & charming space to unwind & relax after a busy day of work or play. Featuring an open-concept layout providing guests the ability to cook a meal & have conversations with others in the adjoining living room. The 2 bedrooms each features a queen size bed & there is a sofa bed for additional guests. Located in town are 3 restaurants, Casey's & Dollar General. Amish Community is a short drive of 14 miles Mark Twain Lake 32 miles Moberly 12 miles

Guest favorite

Home in Bowling Green

4.97 out of 5 average rating, 204 reviews

Peaceful Country Cottage

Traveling for work or pleasure? Enjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Vandalia, Louisiana, Hannibal or Mark Twain Lake. (40 Min). About one hour from St. Louis.

Guest favorite

Cabin in Stoutsville

4.95 out of 5 average rating, 40 reviews

Escape to Mark Twain Lake!

Nestled in the woods is an adorable cabin just seconds away from Middle Fork boat ramp. Just down the road, delve into history at the Mark Twain Birthplace State Historic Site. A short distance further, the majestic Mark Twain State Park reveals the untouched beauty of nature, with the captivating Mark Twain Lake as its centerpiece. For aficionados of history, nature, and adventure, this lakeside haven is an unmatched sanctuary. Every visit here promises a journey etched in memory.

Guest favorite

Cottage in Philadelphia

4.94 out of 5 average rating, 581 reviews

Frogmore Cottage on 5-acre lake, Enjoy Nature!

This Venue is not availble for booking at this time. Maximum 2 people. No pets. Enjoy nature on this five-acre lake on 25 well-manicured acres. Fabulous sunsets! For a tiny house it has a spacious lower level with a vaulted ceiling and upper bedroom loft. Wifi & smart TV. Outdoor activity includes hammocks, swimming, boating (canoe, kayaks, john boat). For fishing we have boats, nets & fish-dressing station (bring poles & bait). Please list accurate number of guests when booking.

Superhost

Rental unit in Hannibal

4.85 out of 5 average rating, 139 reviews

Farmhouse

Enjoy nostalgic downtown Hannibal in this unique apartment located on Main Street just steps from a movie theater, restaurants and bars, shopping, museums, the riverfront, and Mark Twain historic sites. With a private bedroom with flat screen television, living area with sleeper sofa and daybed, and a full kitchen the interior of this rental is sure to charm any visitor. Book for a weekend, a week, or longer.

Guest favorite

Cabin in Monroe City

5 out of 5 average rating, 29 reviews

Mark Twain Lake Cabin

Welcome to our neck of the woods. Our cabin gives you the perfect getaway, being in the great outdoors with all the comforts of home. Less than 10 minutes to Jellystone, Mark Twain Lake, Spaulding Public Beach(on Mark Twain Lake) and Monroe City. Master bedroom has a queen bed. Bedroom 2 has one queen bed, a bunk bed with full and single, and a pull out couch in the living room.

Guest favorite

Home in Quincy

4.94 out of 5 average rating, 267 reviews

❤️Quincy Quarters❤️

Quincy Quarters is a beautifully restored 1880’s Duplex with modern amenities and all the historic charm. This duplex has been home to families for 140 years. Bring your family and your pet and enjoy 140 years of history. Quincy Quarters is close to Oakley Lindsay Center, Blessing Hospital and Quincy University, it is blocks away from South Park and just a couple minutes from downtown Quincy.

Guest favorite

Guesthouse in Paris

4.97 out of 5 average rating, 61 reviews

Salt River Alpacas Guesthouse

Kick back and relax in this newly built guesthouse. Located on a peninsula on Mark Twain Lake, this guesthouse is surrounded by 130 acres of rolling pastures, plenty of woodlands, and the lake on three sides of the property. Whether you enjoy hiking, canoeing/kayaking, fishing, hunting, learning about our alpacas, or you just want a quiet place to relax, this property has it all!

Guest favorite

Cottage in Hannibal

4.97 out of 5 average rating, 118 reviews

The Rose Cottage in historic downtown Hannibal

Located at the tip of historic Main Street in downtown Hannibal and within easy walking distance of many Mark Twain attractions, restaurants, pubs, shopping, entertainment, etc. At the Rose Cottage, we strive to provide guests with a high quality stay in a cozy, relaxing environment where they can easily enjoy all that downtown Hannibal has to offer.

Guest favorite

Farm stay in Hannibal

4.97 out of 5 average rating, 118 reviews

StoneHill Stables

Stonehill stables has been serving families since 1826 when it was known as Stone Hill school house. It is a convenient location for shopping, dining and entertainment. It is the perfect place for families with kids of all ages and also for a romantic retreat for a couple looking for some peace and quiet.