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Vacation rentals in Jefferson County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Jefferson County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Superhost
Tiny home in Pacific
Route 66 railroad shanty, a cozy artsy small space
This 536 s.f. house, believed to have once been a sleeping shanty for railroad crews switching shifts for the night. Fully renovated and updated in 2021 by a local artist, you will find custom metal art throughout, granite countertops and a very warm cabin feel featuring a kitchen and bathroom finished with locally sourced Missouri dark red cedar, 10 minutes from six flags, Purina farms 15 min from hidden valley and 45 min from downtown this place is in a great location and will not disappoint!
$99 per night
Superhost
Home in Dittmer
Honeymoon Suite Camp Skullbone In The Woods
Romantic quiet cozy chalet for two! Vintage décor with all the modern amenities of home. Relax inside to unwind, kick back and watch a movie, surf the web via free wi-fi, curl up with a good book, open up a board game for a friendly challenge or share a drink with that special someone. Want some fresh country air? Lace-up those hiking boots and take like Camp Skullbones. . Enjoy the stars on the intimate deck with the glow from the gas fire pit.
$121 per night
Superhost
Cabin in Imperial
Serenity Log Inn - Log Out and Log Inn to Serenity
Welcome to Serenity Log Inn. This authentic 1930s log cabin is located one mile from the historical town of Kimmswick and 25 miles from St. Louis with easy access to major highways. There is a $30.00 fee per use of the historical fireplace. Fee covers set up, dry wood for burning, fire starter and maintenance, and $18.00 fee first use to cover clean up. To prevent infestation of insects, no outside wood allowed. 24 hr notice required.
$95 per night

Other great vacation rentals in Jefferson County

Superhost
Home in Barnhart
3 Bedroom Ranch By Grassy Field w/ Laundry & Deck
$109 per night
Superhost
Farm stay in Bloomsdale
FUNKS INN-no extra guest fees or cleaning fee
$192 per night
Superhost
Apartment in St. Louis
The Hellbergs, 2 bedr, close to all major hwy.
$57 per night
Superhost
Cottage in Eureka
Beautiful Cottage on Large Private Lot
$191 per night
Superhost
Loft in Festus
The Loft at 12A
$150 per night
Superhost
Home in Bloomsdale
Hop off the highway, Relax!
$78 per night
Superhost
Cabin in Hillsboro
The Shagbark Hickory (Pool, Hot Tub, & Sauna)
$98 per night
Superhost
Home in De Soto
Lake Time! Dock and hot tub.
$200 per night
Superhost
Home in Cadet
2BR House with Hot Tub near Washington State Park!
$91 per night
Superhost
Home in Pacific
Pet Friendly - Private Home - Fenced Yard
$110 per night
Superhost
Cabin in De Soto
Working Farm with 2 bedroom Log Cabin.
$143 per night
Superhost
Townhouse in Barnhart
Cute town house -3 Queen beds
$88 per night

Destinations to explore