House vacation rentals in DeSoto County
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Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool
Home in Punta Gorda
4.96 out of 5 average rating, 131 reviewsPunta Gorda Isles Gem with Saltwater Spool
Oct 11 – 18
Home in Port Charlotte
4.85 out of 5 average rating, 213 reviewsPeaceful Port Charlotte 2Bd/2Ba on water
Jun 1 – 8
Home in Punta Gorda
4.94 out of 5 average rating, 142 reviewsParadise in PG Isles w/gorgeous pool/spa
May 6 – 13
Home in Port Charlotte
4.94 out of 5 average rating, 109 reviewsLuxury Bungalo with Pool in Port Charlotte
Oct 7 – 14
Home in Port Charlotte
4.81 out of 5 average rating, 32 reviewsOasis with pool in the middle of West Coast, FL
Oct 6 – 13
Home in Sebring
4.83 out of 5 average rating, 12 reviewsThe Little Retreat
Jun 17 – 24
Home in Port Charlotte
4.91 out of 5 average rating, 11 reviewsThe Westbrook House
Aug 6 – 13
Home in Sebring
4.81 out of 5 average rating, 27 reviewsRelax, golf and swim at sun n lake retreat
Aug 2 – 9
Weekly house rentals
Home in Arcadia
5.0 out of 5 average rating, 26 reviews"Old Florida" Getaway
Dec 3 – 10
Home in Punta Gorda
4.9 out of 5 average rating, 29 reviewsHouse in Punta Gorda: Hot tub, Patio, Pet Friendly
Sep 8 – 15
Home in Arcadia
5.0 out of 5 average rating, 53 reviewsSly Gator House
Oct 8 – 15
Home in Punta Gorda
5.0 out of 5 average rating, 22 reviewsPunta Paradise: Comfortable Home Near Downtown
May 10 – 17
Home in North Port
5.0 out of 5 average rating, 13 reviewsIggy's Place
Nov 2 – 9
Home in Punta Gorda
4.93 out of 5 average rating, 72 reviewsCozy Cottage in Historic Downtown Punta Gorda
Jun 11 – 18
Home in Sebring
4.96 out of 5 average rating, 25 reviewsLakeFront Sunrise Cottage
Oct 17 – 24
Home in Sebring
4.89 out of 5 average rating, 63 reviewsSecluded and Peaceful Home Nearby Everything
Apr 6 – 13
Private house rentals
Home in Sebring
4.99 out of 5 average rating, 97 reviewsManatee Manor 3/2 House on Lake Sebring!
Jun 21 – 28
Home in Port Charlotte
4.93 out of 5 average rating, 40 reviewsClean home on quiet street with private pool/lanai
Oct 4 – 11
Home in Port Charlotte
5.0 out of 5 average rating, 9 reviewsCharming 2 bdrm Glory Boathouse
Nov 28 – Dec 5
Home in Port Charlotte
5.0 out of 5 average rating, 9 reviewsSunshine Retreat | NEW 4/2, King Bed, Near Beaches
Nov 14 – 21
Home in Sebring
4.82 out of 5 average rating, 11 reviewsSpacious Home w/Skylight in BA
Dec 6 – 13
Home in North Port
5.0 out of 5 average rating, 18 reviewsEntire light filled Florida 2 bedroom/2 bath home
Jun 27 – Jul 4
Home in Port Charlotte
4.96 out of 5 average rating, 45 reviewsFlorida waterfront life
Jul 15 – 20
Home in Port Charlotte
4.97 out of 5 average rating, 79 reviewsPORT CHARLOTTE FLORIDA RETREAT, 2/2, PRIVATE POOL
Aug 4 – 11
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