Vacation rentals in South Roxana

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Top-rated vacation rentals in South Roxana

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Home in Millstadt

4.93 out of 5 average rating, 223 reviews

Deluxe Barndominium | King bed + Pkg

Enjoy the unique historical setting of this recently remodeled Barndominium, just 5min away from DT Millstadt and 20min from DT St. Louis. Learn the old Illinois ways by relaxing in a contemporary decorated barn that was once an honor system farm stand. Blend of comfort, stylish décor & a rich amenity list are there to satisfy your every need. ✔ 2 Comfy Bedrooms (King Bed, Single over Double Bunk) ✔ Fully Equipped Kitchen ✔ Open Living Area ✔ 55’’ Flat-Screen TV ✔ Fast internet See more below

May 21 – 28

$111 per night
Guest favorite

Apartment in Edwardsville

4.91 out of 5 average rating, 223 reviews

Edwardsville Apartment - The Woodland Suite

The apartment in the lower level of the home has recently been renovated, with a walk-out private entrance, a full kitchen & dining area, full bath, bedroom and a cozy living space. Situated just 35 minutes from downtown St Louis, in the safe and affluent community of Edwardsville, this property sits in a quiet cul de sac on a wooded lot right in the heart of the city. We are just a few minutes from the SIUE campus, Edwardsville HS, & I-270. Coffee/restaurants/shops/parks/trails just 2 min away.

Jul 9 – 16

$128 per night
Guest favorite

Home in Granite City

4.98 out of 5 average rating, 119 reviews

Cozy 2-bedroom home minutes from ST. Louis, MO

Welcome to the Sheridan House. This cozy 2-bedroom home is located in a quiet neighborhood. It sets on a corner lot with a large back yard and a parkway across the street. Spend relaxing evenings on the patio, grilling your dinner. Or challenge your partner to a game of ping pong in the basement rec room. Centrally located, you can spend your days exploring attractions in Saint Louis, Mo, Alton and Edwardsville, IL. Just minutes from World Wide Technology Raceway, Busch Stadium, & the Arch.

Oct 12 – 19

$101 per night

Popular amenities for South Roxana vacation rentals

Other great vacation rentals in South Roxana

Guest favorite

Home in Saint Charles

4.98 out of 5 average rating, 483 reviews

301 Guesthouse SuperHost/Shop Discounts/Katy Trail

Nov 6 – 13

$117 per night
Guest favorite

Home in Roxana

4.95 out of 5 average rating, 55 reviews

The House Next Door

May 7 – 14

$131 per night
Superhost

Home in Wood River

5.0 out of 5 average rating, 9 reviews

Cozy 3 bedroom home close to STL

Nov 26 – Dec 3

$110 per night
Guest favorite

Home in Troy

4.98 out of 5 average rating, 44 reviews

No Frills Home on 2 Acres to yourself!

May 21 – 28

$86 per night
Guest favorite

Apartment in Alton

4.87 out of 5 average rating, 55 reviews

Hearth & Home

Dec 31 – Jan 7

$110 per night
Guest favorite

Camper/RV in Edwardsville

4.98 out of 5 average rating, 54 reviews

luxury RV tiny home- 5 acre property- SIUE- STL

Apr 17 – 24

$104 per night
Guest favorite

Home in Alton

4.86 out of 5 average rating, 35 reviews

Quiet, sunny Alton charmer.

Aug 17 – 24

$90 per night
Guest favorite

Apartment in Edwardsville

4.97 out of 5 average rating, 73 reviews

Cozy Historic Downtown Edwardsville Charmer

Dec 17 – 24

$108 per night
Guest favorite

Home in Alton

4.99 out of 5 average rating, 74 reviews

Cozy renovated 2 bdrm cottage w/ dedicated office

Mar 12 – 19

$76 per night
Guest favorite

Home in Granite City

4.93 out of 5 average rating, 41 reviews

"Blue Bliss Retreat in Granite"n

Jun 11 – 18

$86 per night
Guest favorite

Apartment in Alton

4.96 out of 5 average rating, 28 reviews

Todays comfortable & cozy loft.

Jan 30 – Feb 6

$123 per night
Guest favorite

Home in Florissant

5.0 out of 5 average rating, 5 reviews

Recently Renovated Townhome

May 29 – Jun 5

$104 per night

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