Hotel vacation rentals in Santa Cruz Island
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Top-rated hotel rentals in Santa Cruz Island
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz Island hotel rentals
Family-friendly hotel rentals
Hotel room in Puerto Ayora, Santa Cruz Island, Galapagos Islands
4.81 out of 5 average rating, 59 reviewsThe Galapagos Pearl Hotel- Balcony Room #6
Hostel in Galápagos Islands
4.73 out of 5 average rating, 11 reviewsWhite House G.
Boutique hotel in El Garrapatero
4.6 out of 5 average rating, 10 reviewsEnchanted Lodge
Hotel room in Puerto Ayora
4.74 out of 5 average rating, 31 reviewsGalapagos Dreams Doble
Hotel room in Puerto Ayora
4.75 out of 5 average rating, 85 reviewsNelyza's Suites & Adventure
Hotel in Galapagos/Santa Cruz/Puerto Ayora
4.59 out of 5 average rating, 39 reviewsGloria-Galápagos Inn_Triple
Hotel in Puerto Ayora
4.54 out of 5 average rating, 13 reviewsHabitación Twin Familiar
Hostel in Puerto Ayora
4.93 out of 5 average rating, 15 reviewsKING OR TWIN BEDS SUITE WITH BALCONY ON 2ND FLOOR
Hotel rentals with a pool
Hotel in Puerto Ayora
Natura Gardens Galápagos hotel
Hotel in Santa Cruz
Hotel Tortuga Bay EC
Hotel room in Puerto Ayora
5.0 out of 5 average rating, 9 reviewsHotel Coloma Galápagos : Habitación Triple
Hotel room in Puerto Ayora
4.75 out of 5 average rating, 16 reviewsHOTEL COLOMA GALAPAGOS : HABITACION MATRIMONIAL
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS : HABITACION TWIN
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS HABITACION TWIN
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS : HABITACION FAMILIAR
Hotel in Puerto Ayora
4.67 out of 5 average rating, 15 reviewsEconómica y Acogedora Habitación Doble
Hotel rentals with a patio
Hotel in Puerto Ayora
4.61 out of 5 average rating, 18 reviewsHermosa Habitación matrimonial frente al mar.
Room in Puerto Ayora
4.63 out of 5 average rating, 24 reviewsGALAPAGOS DOVE #5
Nature lodge in Santa Cruz
Cabañas El Edén
Hotel in Puerto Ayora
New place to stayA disfrutar una nueva aventura 4 personas
Hotel in Puerto Ayora
New place to stayStandard Room at Hotel Santa Fe
Hotel in Puerto Ayora
Albatros / Deluxe Double Room
Boutique hotel in Puerto Ayora
Spacious & Comfotable Twin Room with Pool
Hotel in Puerto Ayora
Suite matrimonial
Destinations to explore
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- Boutique hotel rentals Galápagos Islands
- Hotel rentals Galápagos Islands
- Boutique hotel rentals Galápagos Islands
- Hotel rentals Galápagos Islands
- Pet-friendly rentals Santa Cruz Island
- Kid-friendly rentals Santa Cruz Island
- Rentals with a hot tub Santa Cruz Island
- Rentals with a patio Santa Cruz Island
- Hostel rentals Santa Cruz Island
- House rentals Santa Cruz Island
- Rentals with pools Santa Cruz Island
- Apartment rentals Santa Cruz Island
- Serviced apartment rentals Santa Cruz Island
- Rentals with beach access Santa Cruz Island
- Waterfront rentals Santa Cruz Island
- Smoking-friendly rentals Santa Cruz Island
- Monthly Rentals Santa Cruz Island
- Bed and breakfasts Santa Cruz Island
- Rentals with breakfast Santa Cruz Island
- Rentals with a washer and dryer Santa Cruz Island
- Rentals with outdoor seating Santa Cruz Island
- Rentals with a fire pit Santa Cruz Island
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