Little Italy, San Diego vacation rentals

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Top-rated vacation rentals in Little Italy, San Diego

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Superhost

Apartment in Downtown San Diego

4.82 out of 5 average rating, 391 reviews

Relaxing Studio Apt in Little Italy

Welcome to our Sunny & Relaxing Studio Apartment in the Heart of Little Italy, San Diego! This Beautifully Appointed Apartment is Perfect For Those Seeking a Tranquil Retreat in a Vibrant Neighborhood. The Studio is Open and Bright, With Large Windows That Let in Plenty of Natural Light. The Decor is Minimal & Tasteful, With Comfortable Furnishings & High-Quality Linens. The Living Area Features a Plush Sofa and Hammock Chair As Well As a Smart TV With Streaming Services For Your Entertainment.

Dec 8 – 15

$137 per night
Guest favorite

Apartment in Mission Hills

4.98 out of 5 average rating, 137 reviews

Clean, Private, Quiet, Centrally Located Apartment

This spacious 1BR/1BA is nestled in Mission Hills, one of San Diego's most historic neighborhoods. We provide comfortable accommodations within walking distance to many restaurants and pubs. We're only minutes away from Old Town, Little Italy, Gas Lamp, the airport and more. We have all the amenities to make you feel at home while you away from home. The neighborhood is quiet and safe. This property is detached with a private entrance. Includes parking. The laundry is shared with our neighbor.

Sep 1 – 8

$123 per night
Superhost

Apartment in Downtown San Diego

4.89 out of 5 average rating, 247 reviews

PENTHOUSE + VIEW DECK Urban Design in Little Italy

Cozy memory foam King-size bed with two additional sleeper sofas! This penthouse suite is located in the heart of San Diego's highest rated neighborhood, Little Italy! Quick and secure access. Boasting over 36 retail establishments within a two block radius! Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Nov 6 – 13

$367 per night

Popular amenities for Little Italy, San Diego vacation rentals

Stay near Little Italy, San Diego's top sights

Waterfront Park114 locals recommend
Maritime Museum of San Diego124 locals recommend
Little Italy Mercato Farmers' Market247 locals recommend
Filippi's Pizza Grotto Little Italy59 locals recommend
The Crack Shack - Little Italy145 locals recommend
Ironside Fish & Oyster207 locals recommend

Other great vacation rentals in Little Italy, San Diego

Superhost

Apartment in San Diego

4.87 out of 5 average rating, 120 reviews

Modern Escape Close to Little Italy

Apr 22 – 29

$92 per night
Guest favorite

Home in North Park

4.92 out of 5 average rating, 398 reviews

Quiet & Walkable North Park Getaway | Hot Tub + AC

$157 per night
Guest favorite

Home in Bunker Hill - Park West

4.95 out of 5 average rating, 391 reviews

Admire Harbor Views from the Porch at a City Gem

Dec 10 – 17

$197 per night
Guest favorite

Condo in San Diego

4.89 out of 5 average rating, 108 reviews

Modern Condo Minutes To Little Italy W/Parking

Aug 26 – Sep 2

$338 per night
Superhost

Apartment in Downtown San Diego

4.92 out of 5 average rating, 134 reviews

Spacious + Sunny 3bd in the Heart of Little Italy!

Dec 1 – 8

$276 per night
Guest favorite

Guesthouse in San Diego

4.91 out of 5 average rating, 409 reviews

Mission Hills Charming suite, walkable to all.

Aug 18 – 23

$84 per night
Guest favorite

Guesthouse in Point Loma Peninsula

4.98 out of 5 average rating, 115 reviews

Private Studio Cottage with Outdoor Patio

Nov 29 – Dec 6

$150 per night
Guest favorite

Home in Hillcrest

4.91 out of 5 average rating, 156 reviews

Hawk's nest - wakeup to nature - Hillcrest

Feb 17 – 24

$90 per night
Guest favorite

Bungalow in San Diego

4.96 out of 5 average rating, 429 reviews

Sweet Home Stay - Modern Hillcrest Bungalow

Apr 22 – 27

$124 per night
Guest favorite

Guest suite in San Diego

4.94 out of 5 average rating, 553 reviews

Private Hideaway, Shelter Island, Beach & Bay

Nov 17 – 24

$96 per night
Guest favorite

Loft in Downtown San Diego

4.96 out of 5 average rating, 619 reviews

Room A at The Dutra Inn - Little Italy

May 24 – 31

$276 per night
Superhost

Home in Downtown San Diego

5.0 out of 5 average rating, 5 reviews

1920's Craftsman Cottage 1bd

Mar 27 – Apr 3

$129 per night

Other great vacation rentals in Little Italy, San Diego

Superhost

Home in Downtown San Diego

4.89 out of 5 average rating, 27 reviews

Stylish Studio walking distance to Little Italy

Dec 27 – Jan 3

$112 per night
Superhost

Apartment in Downtown San Diego

4.96 out of 5 average rating, 50 reviews

Perfect Downtown Studio w/ AC, Netflix & WiFi

Dec 10 – 17

$153 per night
Guest favorite

Townhouse in San Diego

4.94 out of 5 average rating, 68 reviews

Luxury Home in #1 Downtown Location w/Parking

Dec 12 – 19

$491 per night
Guest favorite

Home in San Diego

4.99 out of 5 average rating, 72 reviews

Peaceful Casita in South Park

Jan 18 – 25

$111 per night
Superhost

Townhouse in Downtown San Diego

4.82 out of 5 average rating, 88 reviews

Contemporary, Fully Renovated Loft in Little Italy

Jun 21 – 28

$306 per night
Superhost

Loft in Downtown San Diego

4.83 out of 5 average rating, 6 reviews

Contemporary Loft with Harbor & City Views

Oct 6 – 13

$270 per night
Guest favorite

Home in San Diego

5.0 out of 5 average rating, 7 reviews

Little Italy Historical Oasis! Newly Renovated!

Oct 16 – 23

$486 per night
Guest favorite

Guesthouse in San Diego

4.98 out of 5 average rating, 54 reviews

King Bed Suite Minutes to DT/Beaches

May 27 – Jun 1

$127 per night
Guest favorite

Apartment in Bunker Hill - Park West

5.0 out of 5 average rating, 43 reviews

Literal neighbor to Balboa Park!

Jun 4 – 11

$314 per night
Guest favorite

Guest suite in Coronado

5.0 out of 5 average rating, 33 reviews

Sunny Relaxing Studio in Beautiful Coronado

Sep 4 – 11

$130 per night
Superhost

Condo in Downtown San Diego

4.89 out of 5 average rating, 66 reviews

NEW Stylish❤️ of Downtown Little Italy w Parking/AC

Oct 10 – 17

$212 per night
Guest favorite

Guesthouse in San Diego

4.98 out of 5 average rating, 64 reviews

Captivating Casita in Historic Mission Hills

Feb 25 – Mar 4

$121 per night

Quick stats about vacation rentals in Little Italy, San Diego

Total rentals

390 properties

Rentals with a pool

70 properties have a pool

Pet-friendly rentals

120 properties allow pets

Family-friendly rentals

160 properties are a good fit for families

Total number of reviews

27K reviews

Nightly prices starting at

$10 before taxes and fees

Destinations to explore

  1. Airbnb
  2. United States
  3. California
  4. San Diego County
  5. San Diego
  6. Little Italy