Colleton County vacation rentals
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Top-rated vacation rentals in Colleton County
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Barn in Early Branch
5.0 out of 5 average rating, 101 reviewsUnique escape! 7 acres of woodsy paradise
Escape to Grays Inn - a peaceful and private setting located in the beautiful South Carolina Low Country! 7 acres all to yourself with woods surrounding the spacious yet cozy barndominium. Ideal for visiting hunters 🦌 , stargazers 💫 , tourists 📸 , golfers 🏌️♂️, or anyone desiring a peaceful escape🌲. Clean, newly renovated and furnished with unique decor. Secluded community not far from wildlife management areas, The Congaree Golf Club, and convenient enough for day trips to Low Country hotspots.
Nov 15 – 22
Guest suite in Beaufort
4.96 out of 5 average rating, 505 reviewsShady Rest #1 near historic downtown Beaufort
Nestled among oaks, this secure, private suite is attached to our home with a separate entrance. We're close to great views, restaurants and shopping, family-friendly activities, nightlife, and the beach. You’ll love our place because of the coziness, the views, and especially the location. It's about a mile from downtown Beaufort, adjacent to the Spanish Moss Biking and Hiking Trail, 6 miles from Parris Island MCRD, convenient to Hilton Head Island, and halfway between Charleston and Savannah.
Sep 21 – 28
Guesthouse in Beaufort
4.96 out of 5 average rating, 206 reviewsSunset River House
Our quaint little River House rests on the beautifully natural marsh grass banks of the Whale Branch River in a quiet rural neighborhood. It is located only 9 miles from Historic Downtown Beaufort and 15 miles from Parris Island Marine Corps Recruit Depot. Hunting Island State Park's sandy beaches, nature tails, and lighthouse tours are a scenic 40 minute drive away. You can swim, fish, kayak or go boating right from the dock in our own back yard. When you arrive; you won't want to leave!
Jan 19 – 26
Vacation rentals for every style
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Popular amenities for Colleton County vacation rentals
Other great vacation rentals in Colleton County
Apartment in Beaufort
4.96 out of 5 average rating, 253 reviewsThe Harrington - Historic Downtown Beaufort
Oct 21 – 28
Farm stay in Ridgeland
4.97 out of 5 average rating, 427 reviewsGlamping on an off grid farm.
May 28 – Jun 4
Home in Beaufort
4.9 out of 5 average rating, 120 reviewsAlways Welcome-Downtown Beaufort
Nov 5 – 12
Bungalow in Beaufort
4.97 out of 5 average rating, 155 reviewsVintage Cottage near downtown Beaufort
Dec 6 – 13
Bus in Hollywood
4.85 out of 5 average rating, 147 reviewsRETRO & FUN 1989 Skoolie Bus Luxury Experience
May 8 – 15
Apartment in Summerville
4.91 out of 5 average rating, 148 reviewsFull Kitchen, 2 Bed, 2 Bath W/ Laundry & Fish Pond
Aug 30 – Sep 6
Home in Beaufort
4.98 out of 5 average rating, 171 reviewsThe Fiddler House - close to P.I. & Downtown Bft
Nov 2 – 9
Guesthouse in Beaufort
4.94 out of 5 average rating, 227 reviewsCozy private guest house
May 8 – 15
Cottage in Beaufort
4.97 out of 5 average rating, 123 reviewsPeaceful River Retreat Near Historic District
Oct 9 – 16
Condo in Edisto Island
4.91 out of 5 average rating, 119 reviews422 Oristo Lodge
Nov 27 – Dec 4
Cottage in Beaufort
4.97 out of 5 average rating, 219 reviewsLovely Cottage in Beaufort w/ State Park Beach Pas
Sep 21 – 28
Home in Beaufort
4.98 out of 5 average rating, 118 reviewsRestored 1889 Historic Cottage
Jan 2 – 9
Other great vacation rentals in Colleton County
Home in Walterboro
5.0 out of 5 average rating, 45 reviewsThe Cozy Casa
Jul 3 – 10
Tiny home in Summerville
5.0 out of 5 average rating, 22 reviewsCountry Cottage Retreat
Apr 12 – 19
Tiny home in Beaufort
4.92 out of 5 average rating, 65 reviewsCheerful tiny close to Parris Island & downtown
Nov 1 – 8
Home in Summerville
5.0 out of 5 average rating, 31 reviewsBeautiful 2 Bedroom cottage in Summerville, SC
Oct 6 – 13
Home in Summerville
4.97 out of 5 average rating, 31 reviewsGuest House/Villa
Jun 21 – 28
Cottage in Dorchester County
4.81 out of 5 average rating, 16 reviewsRelaxing 2-bedroom cottage, Dorchester, S.C.
Sep 15 – 22
Home in Branchville
4.93 out of 5 average rating, 28 reviewsEdisto River Turnhole Getaway
Oct 11 – 16
Guesthouse in Seabrook
5.0 out of 5 average rating, 42 reviewsAdorable guesthouse outside Beaufort
Apr 15 – 22
Guesthouse in Ridgeville
4.91 out of 5 average rating, 23 reviewsCute Frog
Oct 13 – 20
Home in Saint Helena Island
4.99 out of 5 average rating, 85 reviewsThe Tidewatch: Beachfront Retreat on Harbor Island
Feb 11 – 18
Cottage in Edisto Island
4.83 out of 5 average rating, 80 reviewsEscape to Edisto on the Creek
Sep 4 – 11
Home in Ridgeland
4.88 out of 5 average rating, 51 reviewsBeautiful Coastal Cottage Hideaway - entire home
Jul 26 – Aug 2
Destinations to explore
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